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[CAS NO. 837-52-5] 7-Chloro-4-(piperazin-1-yl)quinoline
| Ships within | Stock | Price | Qty | Total |
Please click "REQUEST A QUOTE" button if there is no stock, or you need other sizes or custom synthesis.
| Catalog: | HY-W020111 |
| Brand: | MCE |
| CAS: | 837-52-5 |
Overview
| MDL | MFCD01476123 |
|---|---|
| Molecular Weight | 247.72 |
| Molecular Formula | C13H14ClN3 |
| SMILES | ClC1=CC2=C(C(N3CCNCC3)=CC=N2)C=C1 |
Summary
7-Chloro-4-(piperazin-1-yl)quinolone is an important scaffold in medicinal chemistry. 7-Chloro-4-(piperazin-1-yl)quinolone is a potent sirtuin inhibitor and also inhibits the serotonin uptake ( IC 50 of 50 μM). 7-Chloro-4-(piperazin-1-yl)quinolone exhibits antimalarial activity on D10 and K1 strains of P. falciparum with IC 50 s of 1.18 μM and 0.97 μM, respectively [1] .
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : 16.67 mg/mL ( 67.29 mM ; ultrasonic and warming and heat to 60°C)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 4.0368 mL | 20.1841 mL | 40.3682 mL |
| 5 mM | 0.8074 mL | 4.0368 mL | 8.0736 mL |
| 10 mM | 0.4037 mL | 2.0184 mL | 4.0368 mL |
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