[CAS NO. 85031-59-0]  Dihydroartemisinic acid

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PRODUCTS SPECIFICATIONS [85031-59-0]

Catalog
HY-N4106
Brand
MCE
CAS
85031-59-0

DESCRIPTION [85031-59-0]

Overview

MDLMFCD16876168
Molecular Weight236.35
Molecular FormulaC15H24O2
SMILESOC([C@@H]([C@@]1([H])[C@]2([H])[C@](CCC(C)=C2)([H])[C@H](C)CC1)C)=O

For research use only. We do not sell to patients.

Summary

Dihydroartemisinic acid (Dihydroqinghao acid) is a biosynthetic precursor to the antimalarial agent Artemisinin [1] .


IC50 & Target

Plasmodium


Appearance

Solid



Shipping

Room temperature in continental US; may vary elsewhere.


Storage

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)


Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 423.10 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.2310 mL 21.1551 mL 42.3101 mL
5 mM 0.8462 mL 4.2310 mL 8.4620 mL
10 mM 0.4231 mL 2.1155 mL 4.2310 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 2.5 mg/mL (10.58 mM); Clear solution

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (10.58 mM); Clear solution

  • 3.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 2.5 mg/mL (10.58 mM); Clear solution

* All of the co-solvents are available by MCE.