[CAS NO. 852045-46-6]  Flt-3 Inhibitor III

Flt-3 Inhibitor III (compound 4) also inhibits c-Kit, KDR, c-Abl, CDK1, c-Src and Tie-2 with IC ₅₀ values of 0.26 µM, 0.91 µM, 1.2 µM, 2.1 µM, 2.8 µM, and 8.0 µM, respectively ^[1] .
Flt-3 Inhibitor III (compound 4) blocks the proliferation of BaF3-ITD, BaF3-D835/Y, and MV4:11 cells, with IC ₅₀ values of 0.24 µM, 0.76 µM, and 0.052 µM, respectively ^[1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.