[CAS NO. 86377-52-8] GanodericacidY

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Catalog:	HY-125713
Brand:	MCE
CAS:	86377-52-8

Overview

MDL	-
Molecular Weight	454.68
Molecular Formula	C30H46O3
SMILES	CC1(C)[C@@H](O)CC[C@]2(C)C3=CC[C@]4(C)[C@@H]([C@H](C)CC/C=C(C)/C(O)=O)CC[C@](C)4C3=CC[C@@]12[H]

For research use only. We do not sell to patients.

Summary

Ganoderic acid Y is a α-glucosidase inhibitor with an IC ₅₀ of 170 μM for yeast α-glucosidase. Ganoderic acid Y inhibits enterovirus 71 (EV71) replication through blocking EV71 uncoating ^[1] ^[2] .

In Vitro

Ganoderic acid Y significantly inhibits the replication of the viral RNA (vRNA) of EV71 ^[2] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Appearance

Solid

Source

Plants
Polyporaceae
Ganoderma lucidum (Leyss. Ex Fr.) Karst.

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

References

[1] Chen XQ, et al. Lanostane triterpenes from the mushroom Ganoderma resinaceum and their inhibitory activities against α-glucosidase. Phytochemistry. 2018 May;149:103-115.
[2] Zhang W, et al. Antiviral effects of two Ganoderma lucidum triterpenoids against enterovirus 71 infection. Biochem Biophys Res Commun. 2014 Jul 4;449(3):307-12.

Synonyms

Lanosta-7,9(11),24-trien-26-oic acid, 3-hydroxy-, (3β,24E)-

(3β,24E)-3-Hydroxylanosta-7,9(11),24-trien-26-oic acid

Ganoderic acid Y

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