Welcome to Arctom, sign up to enjoy up to 20% OFF

Search in Small Molecules Search in Biologics

Structure Search

Cart - 0 item(s)
$0.00

Your shopping cart is empty!

Chemistry
Bioactive Molecules
Natural Products
ADCs
Antibodies
- Primary Antibodies
- Secondary Antibodies
Multiplex IHC
Material Science
Others

[CAS NO. 88-58-4] 2,5-Di-tert-butylhydroquinone

Ships within

Stock

Price

Qty

Total

SDS

COA

Please click "REQUEST A QUOTE" button if there is no stock, or you need other sizes or custom synthesis.

Catalog:	HY-W012399
Brand:	MCE
CAS:	88-58-4

Overview

MDL	MFCD00008825
Molecular Weight	222.32
Molecular Formula	C14H22O2
SMILES	OC1=CC(C(C)(C)C)=C(O)C=C1C(C)(C)C

For research use only. We do not sell to patients.

Summary

2,5-Di-tert-butylhydroquinone (DTBHQ), the indirect food additive, regulates the activity of 5-lipoxygenase as well as the activity of COX-2 ( IC ₅₀ =1.8 and 14.1 μM for 5-LO and COX-2 , respectively) ^[1] .

IC50 & Target

5-LO

1.8 μM (IC ₅₀ )

COX-2

14.1 μM (IC ₅₀ )

In Vitro

DTBHQ influences arachidonic acid (AA) metabolism in biologically relevant concentrations in vitro ^[1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Appearance

Solid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 449.80 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.4980 mL	22.4901 mL	44.9802 mL
5 mM	0.8996 mL	4.4980 mL	8.9960 mL
10 mM	0.4498 mL	2.2490 mL	4.4980 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.5 mg/mL (11.25 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.5 mg/mL (11.25 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.5 mg/mL (11.25 mM); Clear solution

* All of the co-solvents are available by MCE.

References

[1] Zsofia Kutil, et al. The influence of the quinone antioxidants tert-butylhydroquinone and 2,5-di-tert-butylhydroquinone on the arachidonic acid metabolism in vitro. Food and Agricultural Immunology. Volume 26, 2015-Issue 4.

Synonyms

1,4-Benzenediol, 2,5-bis(1,1-dimethylethyl)-

Hydroquinone, 2,5-di-tert-butyl-

2,5-Bis(1,1-dimethylethyl)-1,4-benzenediol

Santovar O

Dibug

DTBHQ

2,5-Di-tert-butylquinol

Nocrac NS 7

Antage DBH

Naugard 451

DBH

1,4-Dihydroxy-2,5-di-tert-butylbenzene

2,5-Di-tert-butyl-1,4-hydroquinone

Nonflex Alba

2,5-Di-tert-butyl-1,4-benzohydroquinone

2,5-Di-tert-butylhydroquinone

2,5-Di-tert-butyl-1,4-benzenediol

NSC 11

NSC 9886

BHQ

2,5-Dihydroxy-1,4-di-tert-butylbenzene

DBHQ

Alba

2,5-Di-tert-butyl-1,4-dihydroxybenzene

3,6-Di-tert-butylhydroquinone

Antioxidant NS 7

Antioxidant Alba

Antioxidant DBH

2,5-Ditert-butylbenzene-1,4-diol

Request a Quote

Please fill in your details below to request a COA for our product. We will send the COA to the provided email address promptly.

Arctom is a premier supply platform offering over 600K unique items of Building Blocks, Bioactive Molecules, Natural Products, ADC PEG Linkers, Antibodies, and other Research Chemicals for global pharmaceutical, biotech, university, and industrial customers. We accelerate your research by providing better and faster purchasing experience & services.

Information

Shipping
Privacy notice
Terms of Service
About us
Contact us

Customer service

Search
Custom Synthesis

My account

My account
Orders
Addresses
Shopping cart