[CAS NO. 884-33-3] 2-Benzylsuccinic acid

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PRODUCTS SPECIFICATIONS [884-33-3]

Catalog

HY-W044764

Brand

MCE

CAS

884-33-3

DESCRIPTION [884-33-3]

Overview

MDL	MFCD00055798
Molecular Weight	208.21
Molecular Formula	C11H12O4
SMILES	O=C(O)C(CC1=CC=CC=C1)CC(O)=O

For research use only. We do not sell to patients.

Summary

2-Benzylsuccinic acid (DL-Benzylsuccinic acid) is an potent inhibitor of carboxypeptidase A ( CPA ) ^[1] .

Appearance

Solid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 500 mg/mL ( 2401.42 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.8028 mL	24.0142 mL	48.0284 mL
5 mM	0.9606 mL	4.8028 mL	9.6057 mL
10 mM	0.4803 mL	2.4014 mL	4.8028 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 4.17 mg/mL (20.03 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 4.17 mg/mL (20.03 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 4.17 mg/mL (20.03 mM); Clear solution

* All of the co-solvents are available by MCE.

References

[1] Mark P. Wentland, et al. 96-Well Plate Colorimetric Assay for Ki Determination of (+/-)-2-Benzylsuccinic Acid, an Inhibitor of Carboxypeptidase A: A Laboratory Experiment in Drug Discovery. J Chem Educ. 2004 Mar 1, 81 (3):398.

Synonyms

Butanedioic acid, 2-(phenylmethyl)-

Succinic acid, benzyl-

Butanedioic acid, (phenylmethyl)-

2-(Phenylmethyl)butanedioic acid

Benzylsuccinic acid

2-Benzylsuccinic acid

DL-Benzylsuccinic acid

NSC 20708

α-Benzylsuccinic acid

2-Benzylbutanedioic acid