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[CAS NO. 886-38-4] Diphenylcyclopropenone
| Ships within | Stock | Price | Qty | Total |
Please click "REQUEST A QUOTE" button if there is no stock, or you need other sizes or custom synthesis.
| Catalog: | HY-W014605 |
| Brand: | MCE |
| CAS: | 886-38-4 |
Overview
| MDL | MFCD00001311 |
|---|---|
| Molecular Weight | 206.24 |
| Molecular Formula | C15H10O |
| SMILES | O=C1C(C2=CC=CC=C2)=C1C3=CC=CC=C3 |
Summary
Clinical Trial
| NCT Number | Sponsor | Condition | Start Date | Phase |
|---|---|---|---|---|
| NCT04775979 | Ain Shams University |
Vitiligo
|
January 17, 2021 | Phase 4 |
| NCT05020496 | University of Alabama at Birmingham |
Skin Diseases
|
March 21, 2022 | Early Phase 1 |
| NCT01452594 | Rockefeller University |
Healthy Volunteers
|
October 2011 | |
| NCT03651752 | University of Minnesota|National Alopecia Areata Foundation |
Alopecia Areata
|
November 1, 2019 | Phase 3 |
| NCT01978483 | Innovaderm Research Inc. |
Ultraviolet Rays|Immunosuppression|Hypersensitivity, Delayed|Immune Tolerance+Drug Effects
|
November 2013 | Phase 1 |
| NCT01711684 | Rockefeller University |
Neoplasm Metastasis|Melanoma
|
October 16, 2012 | Phase 1 |
| NCT05481658 | Nicholas Gulati|Icahn School of Medicine at Mount Sinai |
Cutaneous Metastases
|
September 2022 | Phase 1 |
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
DMSO : 100 mg/mL ( 484.87 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 4.8487 mL | 24.2436 mL | 48.4872 mL |
| 5 mM | 0.9697 mL | 4.8487 mL | 9.6974 mL |
| 10 mM | 0.4849 mL | 2.4244 mL | 4.8487 mL |
References
- [1] Yugang Gong, et al. Diphenylcyclopropenone plays an effective therapeutic role by up-regulating the TSLP/OX40L/IL-13 pathway in severe alopecia areata. Exp Dermatol. 2021 Feb;30(2):278-283.
- [2] Zekayi Kutlubay, et al. Assessment of treatment efficacy of diphenylcyclopropenone (DPCP) for alopecia areata. Turk J Med Sci. 2020 Dec 17;50(8):1817-1824.
Synonyms
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