[CAS NO. 88901-40-0] Cabenoside D

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Catalog:	HY-N11020
Brand:	MCE
CAS:	88901-40-0

Overview

MDL	-
Molecular Weight	636.86
Molecular Formula	C36H60O9
SMILES	C[C@]12[C@](CC=C3[C@@]2([H])CC[C@@H](C3(C)C)O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)CO)([H])[C@]5([C@](CC1=O)([C@@](CC5)([H])[C@H](C)CC[C@@H](O)C(C)(O)C)C)C

For research use only. We do not sell to patients.

Summary

Cabenoside D (compound 8) is a triterpenoid glycoside, which can be isolated from the methanol extract of lichen root. Cabenoside D shows anti-inflammatory activity and inhibits inflammation induced by 12-O-tetracylacyl hormone-13-acetate (TPA) in mice. Cabenoside D also inhibits TPA-induced Epstein-Barr virus (EBV) early antigen (EBV-EA) activation ^[1] .

In Vitro

Cabenoside D (compound 8) (10-1000 mol ratio/TPA, TPA=32 pmol, 20 ng) dose-dependently inhibits TPA-induced Epstein-Barr virus (EBV) early antigen (EBV-EA) activation ^[1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Cabenoside D (compound 8) (0.6 mg/ear; single dose) inhibits TPA-induced inflammation in mice with the inhibition rate of 66% ^[1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Source

Plants
Cucurbitaceae
Bryonia dioica Bojer

Plants
other families
Caput nigri

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Please store the product under the recommended conditions in the Certificate of Analysis.

References

[1] Ukiya M, et al. Anti-inflammatory and anti-tumor-promoting effects of cucurbitane glycosides from the roots of Bryonia dioica. J Nat Prod. 2002 Feb;65(2):179-83.
[2] Ukiya M, et al. Anti-inflammatory and anti-tumor-promoting effects of cucurbitane glycosides from the roots of Bryonia dioica. J Nat Prod. 2002 Feb;65(2):179-83.

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