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[CAS NO. 94-20-2] Chlorpropamide
| Ships within | Stock | Price | Qty | Total |
Please click "REQUEST A QUOTE" button if there is no stock, or you need other sizes or custom synthesis.
| Catalog: | HY-B1429 |
| Brand: | MCE |
| CAS: | 94-20-2 |
Overview
| MDL | MFCD00079004 |
|---|---|
| Molecular Weight | 276.74 |
| Molecular Formula | C10H13ClN2O3S |
| SMILES | O=S(C1=CC=C(Cl)C=C1)(NC(NCCC)=O)=O |
1 Publications Citing Use of MCE
Summary
Chlorpropamide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). Target: Chlorpropamide belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating β cells of the pancreas to release insulin .Chlorpropamide is not recommended for the treatment of NIDDM as it increases blood pressure and the risk of retinopathy. Up to 80% of the single oral dose of chlorpropramide is metabolized, likely in the liver; 80-90% of the dose is excreted in urine as unchanged drug and metabolites.
Clinical Trial
| NCT Number | Sponsor | Condition | Start Date | Phase |
|---|---|---|---|---|
| NCT00004363 | National Center for Research Resources (NCRR)|Northwestern University |
Diabetes Insipidus|Diabetes Insipidus, Neurohypophyseal
|
December 1995 |
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : ≥ 100 mg/mL ( 361.35 mM )
H 2 O : < 0.1 mg/mL (insoluble)
* "≥" means soluble, but saturation unknown.
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 3.6135 mL | 18.0675 mL | 36.1350 mL |
| 5 mM | 0.7227 mL | 3.6135 mL | 7.2270 mL |
| 10 mM | 0.3614 mL | 1.8068 mL | 3.6135 mL |
Synonyms
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