[CAS NO. 943820-93-7]  Wnt/β-cateninagonist2

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PRODUCTS SPECIFICATIONS [943820-93-7]

Catalog
HY-141873
Brand
MCE
CAS
943820-93-7

DESCRIPTION [943820-93-7]

Overview

MDL-
Molecular Weight272.26
Molecular FormulaC13H12N4O3
SMILESO=C(C1=NOC(C2=CC=CO2)=C1)NCCN3N=CC=C3

For research use only. We do not sell to patients.

Summary

Wnt/β-catenin agonist 2 is a potent Wnt agonist. Wnt/β-catenin agonist 2 activates Wnt/β-catenin signaling and can be used in the research of diseases related to the signal transduction [1] . (From patent WO2007078113A1, compound 39)


In Vitro

Wnt/β-catenin agonist 2 is a activator for β-Catenin in SW480 cell line. Wnt/β-catenin agonist 2 shows effect on differentiation ST2 Cell into osteoblasts [1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)


Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL ( 183.65 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.6730 mL 18.3648 mL 36.7296 mL
5 mM 0.7346 mL 3.6730 mL 7.3459 mL
10 mM 0.3673 mL 1.8365 mL 3.6730 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 2.5 mg/mL (9.18 mM); Clear solution

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 2.5 mg/mL (9.18 mM); Clear solution

* All of the co-solvents are available by MCE.