[CAS NO. 944251-24-5] N3-PEG4-C2-NHSester
PRODUCTS SPECIFICATIONS [944251-24-5]
DESCRIPTION [944251-24-5]
Overview
| MDL | MFCD13184948 |
|---|---|
| Molecular Weight | 388.37 |
| Molecular Formula | C15H24N4O8 |
| SMILES | O=C(ON1C(CCC1=O)=O)CCOCCOCCOCCOCCN=[N+]=[N-] |
Summary
N3-PEG4-C2-NHS ester is a nonclaevable 4-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs) .
IC50 & Target
|
Non-cleavable |
Appearance
Liquid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Pure form | -20°C | 3 years |
|---|---|---|
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : 100 mg/mL ( 257.49 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 2.5749 mL | 12.8743 mL | 25.7486 mL |
| 5 mM | 0.5150 mL | 2.5749 mL | 5.1497 mL |
| 10 mM | 0.2575 mL | 1.2874 mL | 2.5749 mL |
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1.
Add each solvent one by one: 10% DMSO >> 90% PBS
Solubility: 20 mg/mL (51.50 mM); Clear solution; Need ultrasonic
-
2.
-
3.
Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)
Solubility: ≥ 2.5 mg/mL (6.44 mM); Clear solution
-
4.
Add each solvent one by one: 10% DMSO >> 90% corn oil
Solubility: ≥ 2.5 mg/mL (6.44 mM); Clear solution