[CAS NO. 95258-14-3] Yadanziolide A

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PRODUCTS SPECIFICATIONS [95258-14-3]

Catalog

HY-N4210

Brand

MCE

CAS

95258-14-3

DESCRIPTION [95258-14-3]

Overview

MDL	-
Molecular Weight	426.41
Molecular Formula	C20H26O10
SMILES	O[C@@]1([C@H]2O)[C@@]34[C@@]([C@@H](O)[C@H](O)[C@]1(OC4)CO)([H])[C@]([C@@](C(C)=CC5=O)([H])C[C@@]3([H])OC2=O)([C@@H]5O)C

For research use only. We do not sell to patients.

Summary

Yadanziolide A, isolated from the cultivated dry seeds of Brucea javanica , has strong antiviral activities with IC ₅₀ of 5.5 μM against tobacco mosaic virus. Yadanziolide A shows significant antitumor effects ^[1] ^[2] .

IC50 & Target

IC50: 5.5 μM (Tobacco mosaic virus) ^[1]

Appearance

Solid

Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 234.52 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.3452 mL	11.7258 mL	23.4516 mL
5 mM	0.4690 mL	2.3452 mL	4.6903 mL
10 mM	0.2345 mL	1.1726 mL	2.3452 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.5 mg/mL (5.86 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.5 mg/mL (5.86 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.5 mg/mL (5.86 mM); Clear solution

* All of the co-solvents are available by MCE.