[CAS NO. 957513-35-8] ASN03576800

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PRODUCTS SPECIFICATIONS [957513-35-8]

Catalog

HY-113761

Brand

MCE

CAS

957513-35-8

DESCRIPTION [957513-35-8]

Overview

MDL	-
Molecular Weight	285.27
Molecular Formula	C11H11NO6S
SMILES	O=C(O)CS(CC(NC1=CC=C(OCO2)C2=C1)=O)=O

For research use only. We do not sell to patients.

Summary

ASN03576800 could be a potent inhibitor for Ebola virus matrix protein VP40 in process of viral assembly and budding process. ASN03576800 occupies the RNA binding region of VP40 ^[1] .

IC50 & Target

VP40 ^[1]

Appearance

Solid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 125 mg/mL ( 438.18 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.5055 mL	17.5273 mL	35.0545 mL
5 mM	0.7011 mL	3.5055 mL	7.0109 mL
10 mM	0.3505 mL	1.7527 mL	3.5055 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.08 mg/mL (7.29 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.08 mg/mL (7.29 mM); Clear solution

* All of the co-solvents are available by MCE.

References

[1] Tamilvanan T, et al. High-throughput virtual screening and docking studies of matrix protein vp40 of ebola virus. Bioinformation. 2013;9(6):286-92.

Synonyms

Acetic acid, 2-[[2-(1,3-benzodioxol-5-ylamino)-2-oxoethyl]sulfinyl]-

2-[[2-(1,3-Benzodioxol-5-ylamino)-2-oxoethyl]sulfinyl]acetic acid