[CAS NO. 96702-03-3] Ectoine
PRODUCTS SPECIFICATIONS [96702-03-3]
DESCRIPTION [96702-03-3]
Overview
| MDL | MFCD03419286 |
|---|---|
| Molecular Weight | 142.16 |
| Molecular Formula | C6H10N2O2 |
| SMILES | O=C([C@H]1NC(C)=NCC1)O |
Summary
Ectoine is a natural cell protectant, an amino acid derivate produced by bacteria living under extremely harsh environmental conditions. Ectoine serves as an osmoregulatory compatible solute, increasing the hydration of the skin surface and stabilizing lipid layers, which is useful in skincare. Ectoine demonstrates a good safety profile for the treatment of allergic rhinitis [1] [2] .
IC50 & Target
Bacterial [1]
In Vitro
Ectoine (0-5% (w/v); 0-24 h; human erythrocytes) protects the cells from damage caused by SDS treatment [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
| NCT Number | Sponsor | Condition | Start Date | Phase |
|---|---|---|---|---|
| NCT03186755 | Michael Marchand, MD|Université de Montréal|St. Justine´s Hospital |
Conjunctivitis, Allergic|Conjunctivitis, Vernal
|
June 11, 2017 | Phase 4 |
Appearance
Solid
Source
Ethtothiorhodospiru halochloris、Ehalonas elongata
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
H 2 O : 250 mg/mL ( 1758.58 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 7.0343 mL | 35.1716 mL | 70.3433 mL |
| 5 mM | 1.4069 mL | 7.0343 mL | 14.0687 mL |
| 10 mM | 0.7034 mL | 3.5172 mL | 7.0343 mL |
-
1.
Add each solvent one by one: PBS
Solubility: 100 mg/mL (703.43 mM); Clear solution; Need ultrasonic
Synonyms