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[CAS NO. 98-98-6] Picolinic acid
| Ships within | Stock | Price | Qty | Total |
Please click "REQUEST A QUOTE" button if there is no stock, or you need other sizes or custom synthesis.
| Catalog: | HY-I0660 |
| Brand: | MCE |
| CAS: | 98-98-6 |
Overview
| MDL | MFCD00006293 |
|---|---|
| Molecular Weight | 123.11 |
| Molecular Formula | C6H5NO2 |
| SMILES | O=C(O)C1=CC=CC=N1 |
Summary
PCL 016 is a topical antiviral agent, which inhibits adenovirus replication in rabbit.
IC50 & Target
|
Human Endogenous Metabolite
|
In Vivo
Topical 1.5% PCL, 0.8% PCL, 0.369% PCL (pH7), 0.369% PCL (pH4) and 0.5% CDV are significantly more effective than the Control in reducing Ad Positive Cultures/Total (Days 1-14) and the Duration of Ad Shedding in the Ad5/NZW rabbit ocular model. Although not statistically significant, there appears to be a trend toward concentration-dependent efficacy of PCL 016 on the Duration of Ad Shedding. There is no apparent ocular toxicity associated with PCL 016 concentrations [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : ≥ 100 mg/mL ( 812.28 mM )
H 2 O : ≥ 50 mg/mL ( 406.14 mM )
* "≥" means soluble, but saturation unknown.
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 8.1228 mL | 40.6141 mL | 81.2282 mL |
| 5 mM | 1.6246 mL | 8.1228 mL | 16.2456 mL |
| 10 mM | 0.8123 mL | 4.0614 mL | 8.1228 mL |
-
1.
Add each solvent one by one: PBS
Solubility: 100 mg/mL (812.28 mM); Clear solution; Need ultrasonic
-
2.
-
3.
Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)
Solubility: ≥ 2.5 mg/mL (20.31 mM); Clear solution
-
4.
Add each solvent one by one: 10% DMSO >> 90% corn oil
Solubility: ≥ 2.5 mg/mL (20.31 mM); Clear solution
Synonyms
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