[CAS NO. 99-93-4] 4-Hydroxyacetophenone

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PRODUCTS SPECIFICATIONS [99-93-4]

Catalog

HY-Y0073

Brand

MCE

CAS

99-93-4

DESCRIPTION [99-93-4]

Overview

MDL	MFCD00002359
Molecular Weight	136.15
Molecular Formula	C8H8O2
SMILES	CC(C1=CC=C(O)C=C1)=O

For research use only. We do not sell to patients.

Summary

4-Hydroxyacetophenone (P-hydroxyacetophenone) is a key hepatoprotective and choleretic compound in Artemisia capillaris and A. morrisonensis , also has an anti-hepatitis B virus effect and anti-inflammatory effect ^[1] .

Appearance

Solid

Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 734.48 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	7.3448 mL	36.7242 mL	73.4484 mL
5 mM	1.4690 mL	7.3448 mL	14.6897 mL
10 mM	0.7345 mL	3.6724 mL	7.3448 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.5 mg/mL (18.36 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.5 mg/mL (18.36 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.5 mg/mL (18.36 mM); Clear solution

* All of the co-solvents are available by MCE.

References

[1] Ching-Wen C, et al. p-Hydroxyacetophenone suppresses nuclear factor-κB-related inflammation in nociceptive and inflammatory animal models. J Nat Med. 2017 Apr;71(2):422-432.

Synonyms

Ethanone, 1-(4-hydroxyphenyl)-

Acetophenone, 4′-hydroxy-

Acetophenone, p-hydroxy-

1-(4-Hydroxyphenyl)ethanone

4-Acetylphenol

Piceol

Methyl p-hydroxyphenyl ketone

p-Hydroxyacetophenone

p-Hydroxyphenyl methyl ketone

p-Acetylphenol

4′-Hydroxyacetophenone

4-Hydroxyphenyl methyl ketone

p-Acetophenol

1-(4-Hydroxyphenyl)-1-ethanone

Methyl 4-hydroxyphenyl ketone

4-Acetophenol

4-Hydroxyphenylethanone

NSC 3698