[CAS NO. 117857-93-9]  L-CCG-I

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PRODUCTS SPECIFICATIONS [117857-93-9]

Catalog
AS1010902
Brand
Arctom Scientific
CAS
117857-93-9

DESCRIPTION [117857-93-9]

Overview

MDL-
Molecular Weight159.14
Molecular FormulaC6H9NO4
SMILES[H][C@@]1([C@H](N)C(O)=O)[C@@H](C(O)=O)C1

For research use only. We do not sell to patients.

Summary

L-CCG-I is an extended isomer of conformationally restricted glutamate analog. L-CCG-I also is a potent agonist for mGluR2 with an EC 50 value of 0.3 nM. L-CCG-I can be used for the research of mGluR family [1] .


IC50 & Target

mGluR2

0.3 nM (EC 50 )


In Vitro

L-CCG-I has activity for mGluR2 with an EC 50 value of 0.3 nM [1] .
LCCG-I effectively stimulated phosphatidylinositol hydrolysis in mGluR1-expressing cells [1] .
L-CCG-I can inhibit the forskolin-stimulated adenosine 3':5'-cyclic monophosphate (cyclic AMP) accumulation in mGluR2-expressing cells [1] .
L-CCG-I evoked an inhibition of the forskolin-stimulated cyclic AMP production characteristic of mGluR4 [1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Please store the product under the recommended conditions in the Certificate of Analysis.