[CAS NO. 333314-79-7]  HIF1-IN-3

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PRODUCTS SPECIFICATIONS [333314-79-7]

Catalog
AS1037371
Brand
Arctom Scientific
CAS
333314-79-7

DESCRIPTION [333314-79-7]

Overview

MDL-
Molecular Weight412.48
Molecular FormulaC26H24N2O3
SMILESO=C(CCC1=CC=CC=C1)NC(C2=C(O)C3=NC=CC=C3C=C2)C4=CC=C(C=C4)OC

For research use only. We do not sell to patients.

Summary

HIF1-IN-3 (compound F4) is a potent HIF1 inhibitor with an EC 50 value of 0.9 μM. HIF1-IN-3 can be used for researching anticancer [1] .


IC50 & Target

EC 50 : 0.9 μM (HIF1) [1]


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)


Solvent & Solubility

In Vitro:

DMSO : 125 mg/mL ( 303.04 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4244 mL 12.1218 mL 24.2436 mL
5 mM 0.4849 mL 2.4244 mL 4.8487 mL
10 mM 0.2424 mL 1.2122 mL 2.4244 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 2.08 mg/mL (5.04 mM); Clear solution

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 2.08 mg/mL (5.04 mM); Clear solution

* All of the co-solvents are available by MCE.