[CAS NO. 1178-24-1]  3,​5,​6,​7,​8,​3',​4'-​Heptemthoxyflavone

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PRODUCTS SPECIFICATIONS [1178-24-1]

Catalog
AS958688
Brand
Arctom Scientific
CAS
1178-24-1

DESCRIPTION [1178-24-1]

Overview

MDL-
Molecular Weight432.42
Molecular FormulaC22H24O9
SMILESO=C1C(OC)=C(C2=CC=C(OC)C(OC)=C2)OC3=C(OC)C(OC)=C(OC)C(OC)=C13

For research use only. We do not sell to patients.

Summary

3,5,6,7,8,3',4'-heptamethoxyflavone, a flavonoid in Citrus reticulata peels, exhibits anti-tumor-initiating effect and Anti-neuroinflammatory activity [1] [2] [3] . 3,5,6,7,8,3',4'-heptamethoxyflavone inhibits collagenase activity and increased type I procollagen content in HDFn cells [1] . 3,5,6,7,8,3',4'-heptamethoxyflavone induces brain-derived neurotrophic factor (BDNF) expression via cAMP/ERK/CREB signaling and reduces phosphodiesterase activity in C6 cells [4] .


Appearance

Solid



Shipping

Room temperature in continental US; may vary elsewhere.


Storage

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)


Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL ( 115.63 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3126 mL 11.5628 mL 23.1257 mL
5 mM 0.4625 mL 2.3126 mL 4.6251 mL
10 mM 0.2313 mL 1.1563 mL 2.3126 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: 2.5 mg/mL (5.78 mM); Suspended solution; Need ultrasonic

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 2.5 mg/mL (5.78 mM); Clear solution

* All of the co-solvents are available by MCE.


Synonyms

4H-1-Benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-3,5,6,7,8-pentamethoxy-
Flavone, 3,3′,4′,5,6,7,8-heptamethoxy-
2-(3,4-Dimethoxyphenyl)-3,5,6,7,8-pentamethoxy-4H-1-benzopyran-4-one
3,5,6,7,8,3′,4′-Heptamethoxyflavone
3,3′,4′,5,6,7,8-Heptamethoxyflavone
3′,4′,3,5,6,7,8-Heptamethoxyflavone
NSC 618928
3-Methoxynobiletin
3,5,6,7,8,3′,4′-Heptamethphoxyflavone
2-(3,4-Dimethoxyphenyl)-3,5,6,7,8-pentamethoxychromen-4-one