[CAS NO. 247925-28-6]  18:0mPEG2000PEsodium

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PRODUCTS SPECIFICATIONS [247925-28-6]

Catalog
HY-112760
Brand
MCE
CAS
247925-28-6

DESCRIPTION [247925-28-6]

Overview

MDL-
Molecular Weight2808.74
Molecular FormulaC45H87NNaO11P
SMILESCCCCCCCCCCCCCCCCCC(O[C@](COC(CCCCCCCCCCCCCCCCC)=O)(COP(OCCNC(OCCOC)=O)(O[Na])=O)[H])=O

For research use only. We do not sell to patients.

Summary

PEG2000-DSPE can be used for the preparation of stabilized nucleic acid-lipid particllipid particles (SNALPs). SNALPs represent some of the earliest and best functional siRNA-ABC nanoparticles described [1] .


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

4°C, sealed storage, away from moisture and light

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)


Solvent & Solubility

In Vitro:

DMSO : 10 mg/mL ( 3.56 mM ; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.3560 mL 1.7802 mL 3.5603 mL
5 mM --- --- ---
10 mM --- --- ---
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 1.25 mg/mL (0.45 mM); Clear solution

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 1.25 mg/mL (0.45 mM); Clear solution

* All of the co-solvents are available by MCE.