[CAS NO. 2259318-54-0]  Mal-Phe-C4-VC-PAB-DMEA-PNU-159682

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PRODUCTS SPECIFICATIONS [2259318-54-0]

Catalog
HY-126689
Brand
MCE
CAS
2259318-54-0

DESCRIPTION [2259318-54-0]

Overview

MDL-
Molecular Weight1402.46
Molecular FormulaC70H83N9O22
SMILESC[C@H]1[C@]2([H])[C@](N3[C@]([C@H](OCC3)OC)([H])O2)([H])C[C@](O1)([H])O[C@@H]4C5=C(C[C@](C(COC(N(C)CCN(C)C(OCC6=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCC7=CC=C(N8C(C=CC8=O)=O)C=C7)=O)=O)=O)C=C6)=O)=O)=O)(O)C4)C(O)=C9C(C(C%10=C(OC)C=CC=C%10C9=O)=O)=C5O

For research use only. We do not sell to patients.

Summary

Mal-Phe-C4-VC-PAB-DMEA-PNU-159682, a agent-linker conjugate for ADC , consists the ADC linker Mal-Phe-C4-VC-PAB and a potent ADC cytotoxin DMEA-PNU-159682. DMEA-PNU-159682 includes metabolites of nemorubicin (MMDX) from liver microsomes and ADC cytotoxin PNU-159682 [1] .


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