MDL | - |
---|---|
Molecular Weight | 897.76 |
Molecular Formula | C34H54Cl2N10O14 |
SMILES | N=C(NC(NCCCCCCNC(NC(NC1=CC=C(Cl)C=C1)=N)=N)=N)NC2=CC=C(Cl)C=C2.O[C@H]([C@@H](O)C(O)=O)[C@H](O)[C@H](O)CO.O[C@H]([C@@H](O)C(O)=O)[C@H](O)[C@H](O)CO |
Chlorhexidine digluconate is a chlorophenyl biguanide with broad antibacterial action against both Gram (+) and (-) bacteria and fungi . Chlorhexidine digluconate is a broad-spectrum antiseptic and disinfectant. Chlorhexidine digluconate is effective to prevent and control infectious diseases of the mouth by killing bacteria in saliva and tongue. Chlorhexidine digluconate is a cytotoxic agent and induces cell necrosis and apoptosis [1] [2] [3] .
Chlorhexidine digluconate (0.00001%, 0.00005%, 0.0001%, 0.0005%; 1-4 h) demonstrates a cytotoxic effect on CHO cells. Chlorhexidine digluconate reduces the activity of dehydrogenase of CHO cells in a dose-dependent and a time-dependent manner
[2]
.
Chlorhexidine digluconate (0.00005%, 0.0001%, 0.0005%; 1 h) causes the amount of cell
apoptosis
of about 1.62%, 5.51%, and 5.47%, respectively. The amount of cell necrosis was 2.38%, 8.62%, and 22.50%, respectively
[2]
.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Cell Cytotoxicity Assay [2]
Cell Line: | Chinese hamster ovary cells |
Concentration: | 0.00001%, 0.00005%, 0.0001%, 0.0005% |
Incubation Time: | 1, 2, 4 h |
Result: | Demonstrated a cytotoxic effect on CHO cells. |
Apoptosis Analysis [2]
Cell Line: | Chinese hamster ovary cells |
Concentration: | 0.00005%, 0.0001%, 0.0005% |
Incubation Time: | 1 h |
Result: |
After a 1 hour treatment, the amount of cell apoptosis was about 1.62%, 5.51%, and 5.47%, respectively.
The amount of cell necrosis was 2.38%, 8.62%, and 22.50%, respectively. |
Chlorhexidine gluconate (0.05%, 0.025%; One-time intraperitoneal injection) with 0.05% lavage has significantly lower incidence of postoperative intra-abdominal abscesses compared with the mice that had saline lavage only [1] .
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Animal Model: | Male Imprinting Control Region (ICR) mice at 6 to 8-wk-old (body weight, 25g) [1] |
Dosage: | Chlorhexidine gluconate 0.05% and 0.025% |
Administration: | One-time intraperitoneal injection |
Result: | With 0.05% lavage had significantly lower incidence of postoperative intra-abdominal abscesses compared with the mice that had saline lavage only. |
NCT Number | Sponsor | Condition | Start Date | Phase |
---|---|---|---|---|
NCT03859908 | Universidad de El Salvador |
Surgical Site Infection
|
April 5, 2019 | Phase 4 |
NCT04485312 | Cairo University |
Disabilities Multiple
|
July 15, 2020 | Not Applicable |
NCT01411891 | University of Wisconsin, Madison |
Catheter Infections|Spinal Catheter (Epidural) (Subdural); Complications, Infection or Inflammation
|
August 2011 | Phase 4 |
NCT02386592 | Boston University|University Teaching Hospital, Lusaka, Zambia|Zambia Center for Applied Health Research and Development|Children´s Hospital of Philadelphia |
Neonatal Sepsis|Neonatal Mortality
|
September 1, 2015 | Not Applicable |
NCT00719329 | Johns Hopkins Bloomberg School of Public Health|Dhaka Shishu Hospital|Shimantik, Bangladesh|Thrasher Research Fund |
Infection
|
August 2008 | Not Applicable |
NCT03140254 | CareFusion |
Preoperative Skin Preparation
|
September 2016 | Phase 2 |
NCT04794231 | Istanbul Medeniyet University |
Catheter-Related Infections
|
May 1, 2018 | Not Applicable |
NCT04438434 | University of Milan|BMG Pharma |
Impacted Third Molar Tooth|Healing Surgical Wounds
|
June 2020 | Phase 3 |
NCT01740245 | AGUNCO Obstetrics and Gynecology Centre |
Antisepsis Regimen After Surgical Treatment of HPV Infected Lesions
|
Phase 4 | |
NCT03139409 | Cairo University |
Recurrent Caries Incidence
|
July 20, 2017 | Not Applicable |
NCT00272675 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)|Onze Lieve Vrouwe Gasthuis |
Nosocomial Infection|Respiratory Tract Infection|Surgical Site Infection
|
August 2003 | Phase 2|Phase 3 |
NCT02756377 | Islamic Azad University, Tehran |
Periodontal Diseases
|
May 2014 | Phase 2|Phase 3 |
NCT03925155 | Montefiore Medical Center |
Cesarean Section Complications
|
May 1, 2020 | Phase 3 |
NCT01286168 | Mayo Clinic|University of California, San Francisco|Ethicon, Inc. |
Nonmalignant Breast Conditions|Breast Cancer
|
May 2011 | Phase 2 |
NCT01906242 | Federal University of Pelotas |
Denture Hygiene Protocol
|
April 2013 | Not Applicable |
NCT05178823 | Semmelweis University |
Gingival Diseases|Caries
|
June 1, 2017 | Phase 4 |
NCT03295461 | Postgraduate Institute of Dental Sciences Rohtak |
Periodontitis
|
March 2013 | Not Applicable |
NCT02788786 | Johns Hopkins Bloomberg School of Public Health|Bill and Melinda Gates Foundation |
Periodontitis|Premature Birth of Newborn
|
June 27, 2016 | Phase 2 |
NCT02215460 | University of Taubate|Fundação de Amparo à Pesquisa do Estado de São Paulo |
Periodontitis
|
April 2012 | Phase 4 |
NCT02252588 | University of Minnesota|Veterans Medical Research Foundation|Flight Attendant Medical Research Institute |
Chronic Obstructive Pulmonary Disease
|
September 1, 2014 | Phase 2 |
NCT05679661 | Huang YuGuang|Peking Union Medical College Hospital |
Postoperative Complications
|
February 6, 2023 | Not Applicable |
NCT03919942 | Federal University of the Valleys of Jequitinhonha and Mucuri |
Pericoronitis
|
April 19, 2019 | Not Applicable |
NCT04376268 | Yuzuncu Y?l University |
Impacted Third Molar Tooth
|
January 15, 2019 | Phase 4 |
NCT01040286 | Dexcel Pharma Technologies Ltd. |
Periodontitis
|
August 2009 | Phase 2 |
NCT03801187 | Università Vita-Salute San Raffaele |
Peri-implantitis
|
July 2, 2018 | Not Applicable |
NCT03412734 | TriHealth Inc. |
Hysterectomy
|
May 18, 2018 | Phase 4 |
NCT02294604 | Taipei Medical University Shuang Ho Hospital |
Hand Disinfection
|
April 2015 | Not Applicable |
NCT02526667 | Medline Industries |
Surgery
|
August 2015 | Phase 3 |
NCT01079663 | Dexcel Pharma Technologies Ltd. |
Peri-implantitis
|
March 2010 | Phase 2 |
NCT04845672 | Marmara University |
Skin Microbiota
|
February 15, 2021 | Not Applicable |
NCT06002295 | Sheikh Zayed Federal Postgraduate Medical Institute |
Neonatal Sepsis|Omphalitis
|
September 12, 2020 | Phase 2 |
NCT05741866 | The University of Queensland|Queensland Children´s Hospital|Royal Brisbane and Women´s Hospital|University Hospital of Poitiers|Griffith University |
Vascular Access Complication|Device Related Infection|Device Related Sepsis|Device Site Reactions|Catheter Infection|Catheter Complications|Catheter-Related Infections|Catheter Related Complication|Occlusive Dressings|Wound Infection|Wound of Skin|Wound
|
May 3, 2023 | Not Applicable |
NCT03385304 | University of Maryland, Baltimore|McMaster University|United States Department of Defense |
Surgical Site Infection|Unplanned Fracture-Related Reoperation|Open Appendicular Fracture
|
April 8, 2018 | Phase 4 |
NCT01122862 | GlaxoSmithKline |
Healthy Subjects
|
April 2010 | Phase 2 |
NCT01090479 | Northwestern University|Sage Products, Inc. |
Post-operative Surgical Site Infections
|
January 2010 | Not Applicable |
NCT04899986 | University of Pavia |
Peri-implant Mucositis
|
May 15, 2021 | Not Applicable |
NCT05797818 | Ondine Biomedical Inc. |
Healthcare Associated Infection|Nosocomial Infection|Surgical Site Infection
|
January 10, 2023 | Phase 1|Phase 2 |
NCT03384537 | Cairo University |
Dental Diseases
|
June 1, 2024 | Early Phase 1 |
NCT01750801 | Federal University of Minas Gerais |
Gingivitis|Periodontitis|Plaque|Inflammation
|
February 2013 | Phase 3 |
NCT03484507 | University of California, San Francisco|Research to Prevent Blindness |
Acanthamoeba Keratitis
|
January 1, 2018 | Phase 2 |
NCT02202577 | Case Western Reserve University |
Surgical Site Infection
|
March 2014 | Not Applicable |
NCT05304338 | Ataturk University |
Oral Hygiene|Dental Plaque
|
October 10, 2021 | Not Applicable |
NCT05254275 | University of Pavia |
Peri-implant Mucositis
|
March 22, 2022 | Not Applicable |
NCT02115776 | University of Santiago de Compostela|Hospital Clinico Universitario de Santiago |
Bacteremia
|
January 2014 | Not Applicable |
NCT02624622 | University of New Mexico|University of Nairobi |
Omphalitis
|
March 2015 | Not Applicable |
NCT01349192 | University of North Carolina, Chapel Hill|CF Therapeutics Development Network Coordinating Center|Seattle Children´s Hospital|Washington University School of Medicine|University of Washington|University of Colorado, Denver|Baylor College of Medicine|University of Alabama at Birmingham|Cook Children´s Medical Center|University of Michigan|University of Florida|University of Texas Southwestern Medical Center|Children´s Hospital Medical Center, Cincinnati|St. Louis Children´s Hospital |
Cystic Fibrosis|Methicillin-resistant Staphylococcus Aureus
|
April 2011 | Phase 2 |
NCT01270776 | Mount Sinai Hospital, Canada|The Physicians´ Services Incorporated Foundation |
Anti-infecting Agents, Local
|
January 2011 | Not Applicable |
NCT04385680 | Zagazig University |
Postpartum Endometritis|Wound Infection|Chlorhexidine Adverse Reaction|Postoperative Fever
|
May 15, 2020 | Phase 1|Phase 2 |
NCT03431701 | Makassed General Hospital |
Vaginal Scrubbing
|
February 8, 2018 | Not Applicable |
NCT00006075 | National Institute of Allergy and Infectious Diseases (NIAID) |
HIV Infections
|
Phase 2 | |
NCT04654182 | Molnlycke Health Care AB|BioScience Laboratories, Inc. |
Hand Hygiene
|
November 30, 2020 | Phase 4 |
NCT02589067 | Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center|Thrasher Research Fund |
S. Aureus Oropharyngeal Colonization
|
October 2015 | Phase 2 |
NCT03571100 | MidAtlantic Retina|Wills Eye |
Age-related Macular Degeneration|Diabetic Vascular Diseases|Proliferative Retinopathy|Retina Vein Occlusion
|
May 7, 2018 | Early Phase 1 |
NCT00608959 | Cadence Pharmaceuticals|Cadence |
Infection
|
May 2008 | Phase 3 |
NCT02402907 | Icahn School of Medicine at Mount Sinai |
Chlorhexidine Gluconate Cloths|Infection; Cesarean Section|Infectious Morbidity|Surgical Site Infections|Endometritis
|
April 2015 | Not Applicable |
NCT03348917 | Mundipharma Manufacturing Pte Ltd.|Genome Institute of Singapore |
Skin Health
|
December 28, 2017 | Phase 4 |
NCT03526770 | Dr Meru S|Uttaranchal Dental & Medical Research Institute |
Saliva Altered|Oral Hygiene|pH|Tooth Structure; Disorder
|
May 28, 2018 | Not Applicable |
NCT01886001 | University of Virginia |
Colonization
|
November 2012 | Not Applicable |
NCT04430998 | University of Milan|Azienda Farmaceutica Italiana SRL |
Periodontal Index|Pain
|
June 2020 | Phase 3 |
NCT02153658 | Ministry of Health, Rwanda |
Odor Levels of Study Arms
|
November 2013 | Not Applicable |
NCT02753387 | Rennes University Hospital |
Bacterial Infection
|
May 23, 2016 | Phase 3 |
NCT05312606 | University of Pavia |
Periodontal Diseases
|
April 4, 2022 | Not Applicable |
NCT02282605 | Destiny Pharma Plc |
Staphylococcus Aureus Infection
|
September 2014 | Phase 1|Phase 2 |
NCT01382446 | St. Joseph´s Hospital and Medical Center, Phoenix|3M |
Ventilator Associated Pneumonia
|
July 2010 | Not Applicable |
NCT04032548 | Mahsa University |
Gingivitis
|
February 18, 2019 | Not Applicable |
NCT05069246 | Ishrat Rahman|Princess Nourah Bint Abdulrahman University |
Gingivitis
|
December 8, 2020 | Phase 2 |
NCT02545244 | Sri Hasanamba Dental College and Hospital |
Gingivitis
|
February 2015 | Phase 3 |
NCT02032394 | Mashhad University of Medical Sciences |
Urinary Tract Infection|Nosocomial Infection|Bacteriuria
|
July 2013 | Phase 4 |
NCT02949583 | Universidade Estadual da Paraiba |
Gingivitis
|
March 2012 | Not Applicable |
NCT05548361 | Cukurova University|BioGaia AB|Sunstar |
Periodontitis|Chlorhexidine|Probiotic
|
April 1, 2022 | Not Applicable |
NCT01883596 | Sinaloa Pediatric Hospital |
Mechanical Ventilation for More Than 48 Hours.
|
October 2012 | Phase 4 |
NCT03119831 | National and Kapodistrian University of Athens |
Periodontitis|Wound Healing
|
November 2015 | Not Applicable |
NCT03700749 | University of Birmingham|Lagos State University|Universidad Francisco Marroquín|Kigali University Teaching Hospital|Christian Medical College and Hospital, Ludhiana, India|University of Edinburgh|University of the Philippines|King Edward Medical University|University of Witwatersrand, South Africa|Universidad Peruana Cayetano Heredia|Centre National Hospitalier Universitaire|Ndola Teaching Hospital|Hospital Espanol de Veracruz|Tamale Teaching Hospital, Tamale |
Abdominal Surgery|Surgical Site Infection
|
November 29, 2018 | Phase 3 |
NCT00259181 | Hadassah Medical Organization |
Dental Plaque
|
January 2005 | Phase 1 |
NCT01852253 | University Medical Center Groningen |
Periodontal Diseases|Peri-implantitis
|
March 2010 | Not Applicable |
NCT00223002 | University of Saskatchewan |
Asepsis|Analgesia, Epidural|Anesthesia, Epidural
|
November 2004 | Not Applicable |
NCT04485520 | Julieta María Méndez Romero|Universidad Nacional de Caaguazu |
Streptococcus, Other Specified Group|Dental Plaque
|
September 21, 2017 | Not Applicable |
NCT04884464 | University of Urbino Carlo Bo |
Aphthous Stomatitis
|
September 1, 2018 | |
NCT02560870 | Islamic Azad University, Tehran |
Periodontal Diseases
|
March 2014 | Phase 2|Phase 3 |
NCT00234598 | Virginia Commonwealth University|National Institute of Nursing Research (NINR) |
Ventilator Associated Pneumonia
|
March 2002 | Phase 2 |
NCT00682006 | Aga Khan University|John Snow, Inc. |
Omphalitis
|
January 2008 | Phase 3 |
NCT02223520 | Johns Hopkins University|Agency for Healthcare Research and Quality (AHRQ) |
Staph Aureus Colonization|Staph Aureus Infection
|
November 2014 | Not Applicable |
NCT00549393 | Johns Hopkins University|Sage Products, Inc. |
Nosocomial Infections
|
February 2008 | Phase 2|Phase 3 |
NCT02709824 | University of Milan |
Adverse Effect
|
December 2011 | Not Applicable |
NCT03118232 | University of California, Irvine|Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center|University of Massachusetts, Amherst|Agency for Healthcare Research and Quality (AHRQ) |
Hospitalization|Infection
|
April 3, 2017 | Phase 4 |
NCT04756804 | Zurex Pharma, Inc. |
Surgical Site Infection
|
June 21, 2021 | Phase 3 |
NCT05122169 | Seoul National University Hospital |
Vaginal Delivery|Surgical Site Infection
|
December 2021 | Not Applicable |
NCT03331263 | Medline Industries |
Surgical Skin Preparation
|
July 21, 2017 | Phase 1 |
NCT02337192 | University of Sao Paulo |
Dentist-Patient Relations
|
January 2014 | Phase 1 |
NCT02097615 | Universidad de Guanajuato|National Council of Science and Technology, Mexico |
Soft Tissue Infections
|
May 2014 | Phase 4 |
NCT04954313 | University of North Carolina, Chapel Hill|Colgate Palmolive |
Cardiovascular Diseases|Diabetes Type 2
|
September 28, 2021 | Phase 4 |
NCT05841589 | omnia sayed|Ain Shams University |
Dental Caries
|
February 21, 2018 | Not Applicable |
NCT02080403 | Dexcel Pharma Technologies Ltd. |
Peri-Implantitis
|
July 2014 | Phase 3 |
NCT02513784 | Columbia University |
Esophageal Adenocarcinoma|Barrett´s Esophagus|Reflux Esophagitis
|
August 2015 | Not Applicable |
NCT04830969 | State University of New York at Buffalo|Sunstar, Inc. |
Diabetes Mellitus, Type II|Periodontitis
|
November 8, 2016 | Phase 2 |
NCT01720797 | University of Florida|AlevoLogic LLC |
Malocclusion
|
February 2013 | Not Applicable |
NCT03731780 | Cairo University |
Dental Caries
|
December 2018 | Not Applicable |
NCT03305159 | Northwestern University |
Surgical Preparation of the Vagina
|
August 1, 2017 | Phase 4 |
NCT05312593 | University of Pavia |
Peri-implant Mucositis
|
April 5, 2022 | Not Applicable |
NCT04399161 | Dr. Krupa NC|JSS Dental College And Hospital |
Cariostatic Agents|Mouthwashes
|
February 15, 2017 | Phase 2|Phase 3 |
NCT01030666 | Peter Eickholz|Heidelberg University|Dr. August Wolff GmbH & Co. KG Arzneimittel|Gaba International AG|Goethe University |
Periodontitis
|
April 2007 | Phase 4 |
NCT02131922 | Jagiellonian University |
Periodontitis|Hypertension
|
September 2009 | Not Applicable |
NCT00528008 | Memorial University of Newfoundland|Eastern Health |
Wound Infection
|
December 2007 | Phase 3 |
NCT01919593 | Thammasat University |
Bacteremia
|
January 2012 | Phase 4 |
NCT05187663 | University of Belgrade|Military Medical Academy|Bredent Medical, Helbo |
Peri-Implantitis
|
January 2014 | Not Applicable |
NCT02433899 | Universidade Federal Fluminense |
Gingival Recession
|
October 2010 | Phase 4 |
NCT00136370 | Centers for Disease Control and Prevention|Bill and Melinda Gates Foundation|United States Agency for International Development (USAID)|National Vaccine Program Office |
Infant, Newborn, Diseases|Sepsis|Puerperal Infection
|
April 2004 | Phase 3 |
NCT00121394 | NICHD Global Network for Women´s and Children´s Health|Global Network for Women´s and Children´s Health Research|Bill and Melinda Gates Foundation|RTI International|University of Alabama at Birmingham|Aga Khan University|Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) |
Sepsis|Pregnancy
|
June 2005 | Phase 3 |
NCT03431766 | G. d´Annunzio University |
Bone Resorption|Bacteria Caused Disease
|
November 17, 2015 | Not Applicable |
NCT02375178 | Universidade do Vale do Sapucai |
Periimplantitis|Dental Plaque|Periodontal Diseases|Caries|Oral Surgical Wound Infection
|
August 2014 | Not Applicable |
NCT03957291 | Assiut University |
Disinfectant Causing Toxic Effect
|
August 2019 | Early Phase 1 |
NCT05707221 | University of Baghdad |
Oral Disease
|
April 17, 2022 | Not Applicable |
NCT00597688 | All India Institute of Medical Sciences, New Delhi |
Ventilator Associated Pneumonia
|
November 2007 | Phase 3 |
NCT03836781 | Amirhossein Farahmand|Islamic Azad University, Tehran |
Chronic Periodontitis
|
April 10, 2018 | Phase 2|Phase 3 |
NCT00560599 | Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center|Kaiser Permanente |
Methicillin Resistant Staphylococcus Aureus Skin Infections
|
April 2007 | Phase 3 |
NCT00475930 | Uniformed Services University of the Health Sciences |
Staphylococcus Aureus|Community-Acquired Infections|Staphylococcal Skin Infections
|
May 2007 | Not Applicable |
NCT02414581 | Hospital Regional de Alta Especialidad del Bajio|Universidad de Guanajuato |
Neutropenia
|
April 2015 | Phase 3 |
NCT03787082 | Gladwin, Mark, MD|National Institutes of Health (NIH)|National Heart, Lung, and Blood Institute (NHLBI)|University of Pittsburgh |
Pulmonary Hypertension|Heart Failure With Normal Ejection Fraction|Pulmonary Heart Disease and Diseases of Pulmonary Circulation
|
December 2022 | Phase 1 |
NCT03142607 | Aga Khan University |
Gingivitis
|
February 3, 2017 | Phase 3 |
NCT00271440 | Johns Hopkins Bloomberg School of Public Health|Tribhuvan University, Nepal|Nepal Nutrition Intervention Project Sarlahi |
Bacterial Infection
|
January 2006 | Phase 1|Phase 2 |
NCT00513799 | Washington University School of Medicine |
Abscesses|Furunculosis|Staphylococcus Aureus|Staphylococcal Skin Infections
|
March 2007 | Not Applicable |
NCT01105767 | Henry M. Jackson Foundation for the Advancement of Military Medicine|Centers for Disease Control and Prevention |
Staphylococcus Aureus|MRSA Skin Infections|Staphylococcal Skin Infections
|
May 2010 | Not Applicable |
NCT05258955 | Liaquat National Hospital & Medical College|Liaquat College of Medicine and Dentostry |
Dental Plaque
|
June 3, 2020 | Phase 1 |
NCT02894593 | University of L´Aquila |
Gingivitis|Periodontitis
|
January 2015 | Not Applicable |
NCT02291601 | Medline Industries |
Surgery
|
October 2014 | Phase 3 |
NCT02227485 | Shiraz University of Medical Sciences |
Gingivitis
|
July 2014 | Not Applicable |
NCT04446533 | University of Milan|BMG Pharma |
Periodontitis|Bleeding Gum|Pocket, Periodontal
|
June 2020 | Phase 3 |
NCT01580943 | Universidade do Porto |
Dental Plaque
|
October 2011 | Phase 1|Phase 2 |
NCT04235985 | Molnlycke Health Care AB |
General Skin Cleansing
|
January 23, 2020 | Phase 4 |
NCT02279381 | Aga Khan University|University of Sydney|The International Federation of Red Cross and Red Crescent Societies |
Neonatal Infections
|
November 2014 | Phase 4 |
NCT03401749 | University of Alabama at Birmingham |
Surgical Site Infection
|
November 1, 2018 | Phase 4 |
NCT03773094 | Cairo University |
High Caries Risk Patients|Antimicrobial Effect|Salivary pH|Patient Satisfaction to Taste
|
January 2019 | Phase 2|Phase 3 |
NCT04868513 | Biochemical and Microbiology Laboratory, Faculty of Dentistry, Autonomous University of San Luis Pot |
Pregnant Women
|
January 2015 | Phase 4 |
NCT02391714 | University of New Mexico|Society of Family Planning |
Contraception
|
October 2013 | Not Applicable |
NCT03977324 | Università Vita-Salute San Raffaele |
Peri-Implantitis
|
July 2, 2018 | Not Applicable |
NCT02640469 | NYU Langone Health |
Infection
|
December 2016 | Not Applicable |
NCT03550651 | Government College of Dentistry, Indore |
Mild Gingivitis|Periodontal Diseases|Plaque
|
August 2016 | Not Applicable |
NCT00002431 | Procter and Gamble|NIH AIDS Clinical Trials Information Service |
Candidiasis, Oral|HIV Infections
|
Not Applicable | |
NCT02939092 | Cairo University |
Gingival Bleeding
|
January 2018 | Not Applicable |
NCT02446158 | E-DA Hospital |
Peritoneal Dialysis Catheter Exit Site Infection
|
May 2010 | Phase 4 |
NCT03700788 | University of Southern California |
Apical Periodontitis
|
May 30, 2023 | Phase 3 |
NCT02560155 | Lindenhofgruppe AG|Clinical Trials Unit Bern (CTU)|Lindenhofstiftung|Labormedizinisches Zentrum Dr. Risch |
Orthopedic Disorders|Surgical Site Infection
|
November 2015 | Not Applicable |
NCT04403971 | National Cheng-Kung University Hospital |
Hospital-acquired Pneumonia
|
May 25, 2020 | Not Applicable |
NCT03533166 | Universidad Complutense de Madrid|Dentaid SL |
Peri-implant Mucositis
|
November 4, 2015 | Not Applicable |
NCT03009006 | Cairo University |
Necrotic Pulp
|
January 3, 2017 | Not Applicable |
NCT03915665 | Istituto Ortopedico Galeazzi |
Peri-implant Mucositis
|
April 15, 2019 | Not Applicable |
NCT01902446 | Nicholas M Mohr|University of Iowa |
Wounds and Injuries|Respiratory Failure|Pneumonia, Ventilator-Associated
|
July 2013 | |
NCT00130221 | Cook County Health|Sage Products, Inc.|Centers for Disease Control and Prevention |
Nosocomial Infection|Bacteremia|Sepsis|Pneumonia|Urinary Tract Infection|Clostridium Infection
|
June 2005 | Phase 1 |
NCT04438421 | University of Milan |
Gingivitis|Bleeding Gum
|
June 2020 | Phase 3 |
NCT04656145 | NYU Langone Health |
Drain Site Complication
|
January 1, 2021 | Not Applicable |
NCT00765167 | Colgate Palmolive |
Dental Plaque
|
November 2007 | Phase 3 |
NCT00066950 | University of California, San Francisco|San Ysidro Health Center|University of California, San Diego|San Diego State University |
Dental Caries
|
March 2003 | Phase 3 |
NCT05110001 | University of California, San Francisco|Aravind Eye Care System|National Eye Institute (NEI)|Stanford University|Federal University of São Paulo |
Acanthamoeba Keratitis|Fungal Keratitis
|
August 3, 2022 | Phase 3 |
NCT04505202 | Karabuk University |
Ventilator Associated Pneumonia|Tracheobronchitis
|
April 15, 2019 | Not Applicable |
NCT05206721 | Mansoura University |
Ventilator Associated Pneumonia
|
May 10, 2020 | Early Phase 1 |
NCT02915289 | Richmond University Medical Center |
Wound Infection|Complication, Postoperative
|
December 2016 | Phase 3 |
NCT02395614 | Vanderbilt University Medical Center |
Breast Cancer
|
December 2015 | Not Applicable |
NCT00266448 | Heidelberg University |
MRSA-Colonization
|
January 2001 | Phase 2 |
NCT00417235 | University Hospital, Grenoble|Ministry of Health, France |
Systemic Inflammatory Response Syndrome|Bacteremia
|
January 2007 | Phase 4 |
NCT04770792 | King Abdulaziz University |
Indirect Pulp Treatment
|
April 6, 2019 | Not Applicable |
NCT05828810 | Sunnybrook Health Sciences Centre |
Aseptic Revision Total Hip Arthroplasty|Total Knee Arthroplasty With Exchange of at Least One Prosthetic Component
|
May 2023 | Phase 4 |
NCT04483063 | National Cheng-Kung University Hospital |
C. Acnes|Arthroscopic Rotator Cuff Repair
|
March 23, 2020 | Not Applicable |
NCT03588351 | Ain Shams University |
Necrotic Pulp
|
January 1, 2018 | Not Applicable |
NCT02154594 | Tatyasaheb Kore Dental College |
Gingivitis
|
February 2014 | Phase 4 |
NCT03871777 | University of Plymouth|University of the West of Scotland |
Blood Pressure
|
May 9, 2016 | Not Applicable |
NCT05441605 | Aydin Adnan Menderes University |
Catheter-Associated Infections
|
June 24, 2022 | Not Applicable |
NCT03594513 | Universidade Estadual Paulista Júlio de Mesquita Filho|Fundação de Amparo à Pesquisa do Estado de São Paulo |
Gingival Recession|Tooth Abrasion
|
July 2, 2018 | Not Applicable |
NCT02065414 | Johnson & Johnson Consumer and Personal Products Worldwide |
Gingivitis
|
March 2014 | Phase 4 |
NCT01014143 | Colgate Palmolive |
Dental Plaque
|
August 2007 | Phase 2 |
NCT02326467 | Celeste Chandonnet|Boston Children´s Hospital |
Chlorhexidine Allergy|Infection|Rash
|
February 2016 | Phase 1 |
NCT02126267 | Centro Universitario de Lavras|Federal University of Minas Gerais |
Periodontal Disease|Chronic Periodontitis
|
January 2013 | Not Applicable |
NCT04512638 | Tim Van den Wyngaert|Kom Op Tegen Kanker|University Hospital, Antwerp |
Medication Related Osteonecrosis of the Jaw
|
January 1, 2021 | Phase 4 |
NCT01521260 | University Medical Center Groningen |
Peri-implantitis|Periodontal Disease
|
October 2009 | Not Applicable |
NCT03669224 | Cairo University |
Caries Class Ii
|
November 1, 2019 | Phase 1 |
NCT05855616 | Hospital Universitario Marqués de Valdecilla |
Hemodialysis Catheter Infection
|
November 1, 2020 | Not Applicable |
NCT00972803 | Tabriz University |
Gingivitis
|
May 2008 | Phase 2 |
NCT04009616 | Damascus University |
Oral Health
|
March 1, 2019 | Not Applicable |
NCT05971810 | Peking Union Medical College Hospital|Fujian Provincial Hospital|The Second Hospital of Hebei Medical University|Shenzhen Qianhai Shekou Free Trade Zone Hospital|Ningbo No.2 Hospital|Peking University International Hospital |
Postoperative Complications|Pulmonary Complication
|
August 1, 2023 | Not Applicable |
NCT05974124 | Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia|European School of Advanced Studies in Ophthalmology |
Antiseptics|Microbiota|Conjunctiva
|
November 9, 2022 | Not Applicable |
NCT00731783 | Washington University School of Medicine |
Staphylococcal Skin Infections|Abscesses|Furunculosis|Staphylococcus Aureus|MRSA Infection
|
July 2008 | Not Applicable |
NCT01962493 | GlaxoSmithKline |
Oral Hygiene
|
September 2013 | Phase 4 |
NCT02709785 | St. Louis University|Triumph Pharmaceuticals |
Gingivitis|Periodontitis
|
March 2016 | Not Applicable |
NCT03442023 | Universidad de Guanajuato |
Chlorhexidine|Ventilator Associated Pneumonia
|
February 1, 2019 | Phase 3 |
NCT00448942 | Hunter Holmes Mcguire Veteran Affairs Medical Center|Weill Medical College of Cornell University|Washington University School of Medicine|Johns Hopkins University|University of Tennessee|Centers for Disease Control and Prevention |
Nosocomial Bacteremia|Nosocomial Fungemia|MRSA Colonization|MRSA Infection|VRE Colonization|VRE Infection
|
November 2004 | |
NCT00779246 | Christiana Care Health Services|Sage Products, Inc. |
Staphylococcal Infections
|
June 2008 | Not Applicable |
NCT03372122 | Caroline Scott|Molnlycke Health Care AB |
General Skin Cleansing
|
December 13, 2017 | Phase 4 |
NCT01361997 | Universidad de Guanajuato |
Infectious Diseases
|
June 2011 | Phase 3 |
NCT00896402 | Northwell Health |
Infection
|
July 2014 | Not Applicable |
NCT03883828 | Montefiore Medical Center |
Radiation Dermatitis
|
June 3, 2019 | Phase 2|Phase 3 |
NCT01410682 | Federal University of São Paulo|Fundação de Amparo à Pesquisa do Estado de São Paulo |
Tracheal and Oropharyngeal Colonization by Gram-negative Pathogens
|
June 2005 | Not Applicable |
NCT02219776 | McLaren Health Care |
Post Operative Infection Arthroscopic Shoulder Surgery|Infection
|
September 2015 | Not Applicable |
NCT03003871 | The University of Hong Kong|Tung Wah Hospital |
Stroke
|
April 2013 | Not Applicable |
NCT03141554 | Mundipharma Manufacturing Pte Ltd.|Singapore Polytechnic (SP) |
Oral Health
|
May 5, 2017 | Phase 4 |
NCT02132546 | dott. Lorenzo Bevilacqua|University of Trieste |
Staining Effect of Chlorhexidine
|
February 2011 | Phase 2 |
NCT02029872 | Johns Hopkins University|Robert Wood Johnson Foundation |
MRSA
|
January 2014 | Phase 4 |
NCT01992198 | Erzhen Chen|RenJi Hospital|Ruijin Hospital |
Pancreatitis,Acute Necrotizing
|
July 2012 | Phase 4 |
NCT02222896 | Medline Industries |
Surgery
|
August 2014 | Phase 3 |
NCT02396329 | Ain Shams Maternity Hospital |
Surgical Site Infection
|
June 2014 | Phase 2 |
NCT03513575 | Dr Meru S|Uttaranchal Dental & Medical Research Institute |
Saliva Altered|Oral Hygiene|pH|Tooth Structure; Disorder
|
May 1, 2018 | Not Applicable |
NCT03030989 | University of Chicago |
Stem Cell Transplant Complications
|
January 2017 | Phase 2 |
NCT01036412 | M.D. Anderson Cancer Center |
Head and Neck Cancer
|
December 2009 | Phase 1 |
NCT02077920 | General Hospital of Shenyang Military Region |
Ventilator-associated Pneumonia
|
March 2014 | Phase 2 |
NCT02537964 | Shaare Zedek Medical Center |
Infectious Disease Transmission
|
September 2016 | Not Applicable |
NCT00785200 | University of Chicago|University of Texas Southwestern Medical Center|Sage Products, Inc. |
Methicillin-resistant Staphylococcus Aureus|Skin Diseases, Infectious|Soft Tissue Infections
|
January 2009 | Not Applicable |
NCT00841074 | University of Louisville|National Institute of Dental and Craniofacial Research (NIDCR) |
Pneumonia|Respiratory Infection
|
January 2006 | Phase 1 |
NCT02391077 | Ministry of Health, Rwanda |
Disease Due to Gram-positive Bacteria
|
April 2015 | Phase 1 |
NCT04607785 | Al-Iraqia University |
Gingivitis
|
January 15, 2020 | Early Phase 1 |
NCT01241318 | Boston University|Bill and Melinda Gates Foundation|Ministry of Health, Zambia|Zambia Center for Applied Health Research and Development |
Sepsis
|
February 2011 | Phase 2|Phase 3 |
NCT02943759 | Cairo University |
Periapical Abscess
|
December 1, 2016 | Phase 2|Phase 3 |
NCT03492827 | Peking University Third Hospital |
Esophageal Cancer|Gastric Cancer
|
June 1, 2017 | Not Applicable |
NCT04344236 | NYU Langone Health |
COVID-19
|
April 9, 2020 | Phase 2 |
NCT03423147 | Angela Bianco|Stryker Nordic|Icahn School of Medicine at Mount Sinai |
Cesarean Section|Surgical Site Infection|Nosocomial Infection
|
October 5, 2018 | Phase 2 |
NCT02469311 | LifeBridge Health |
Osteoarthritis|Infection
|
March 2012 | Phase 2 |
NCT04719208 | Augusta University |
Covid19
|
October 6, 2020 | Not Applicable |
NCT03813693 | University of Sao Paulo |
Surgical Site Infection
|
May 2, 2017 | Not Applicable |
NCT01898000 | Government Dental College and Research Institute, Bangalore |
Gingivitis
|
January 2013 | Not Applicable |
NCT04171817 | Johns Hopkins Bloomberg School of Public Health|Children´s Hospital of Philadelphia|University of Pennsylvania|Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) |
Methicillin-resistant Staphylococcus Aureus|Clostridium Difficile|Pseudomonas Aeruginosa
|
May 1, 2023 | Phase 4 |
NCT00867035 | University of California, San Francisco |
Halitosis
|
March 2008 | Not Applicable |
NCT02605382 | Universidade Federal do Rio Grande do Norte |
Mucositis
|
October 2012 | Phase 2 |
NCT04942496 | Molnlycke Health Care AB|BioScience Laboratories, Inc. |
Skin Irritancy Potential
|
June 2021 | Phase 4 |
NCT01425697 | University of Rochester|Sage Products, Inc. |
Surgical Site Infections
|
November 2008 | Not Applicable |
NCT03844776 | Taibah University |
Infection
|
October 2, 2019 | Not Applicable |
NCT03133312 | Metro Health, Michigan |
Infection, Bacterial
|
May 2, 2017 | Phase 4 |
NCT00502476 | Hunter Holmes Mcguire Veteran Affairs Medical Center|Centers for Disease Control and Prevention|Sage Products, Inc. |
Nosocomial Bacteremia|MRSA Colonization|MRSA Infection|VRE Colonization|VRE Infection
|
August 2007 | |
NCT04781478 | University of Pavia |
Periodontal Diseases
|
March 16, 2021 | Not Applicable |
NCT03166163 | Cairo University |
Gingival Bleeding
|
May 20, 2017 | Not Applicable |
NCT04027179 | University of Taubate|Conselho Nacional de Desenvolvimento Científico e Tecnológico |
Periodontitis|Normal Blood Pressure
|
August 2020 | Phase 4 |
NCT04021524 | University of Washington |
Propionibacterium Acnes
|
September 10, 2018 | Phase 4 |
NCT00109616 | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)|United States Agency for International Development (USAID)|Bill and Melinda Gates Foundation |
Neonatal Mortality
|
October 2002 | Phase 3 |
NCT00067340 | University of Washington|National Institute of Dental and Craniofacial Research (NIDCR) |
Dental Caries
|
April 2003 | Phase 3 |
NCT04218799 | University of Maryland, Baltimore|VA Office of Research and Development |
Human Microbiome
|
August 12, 2014 | Phase 4 |
NCT05430308 | Postgraduate Institute of Medical Education and Research |
Medical Thoracoscopy
|
April 18, 2022 | Not Applicable |
NCT05485051 | Hospital do Coracao|Hospital Sírio-Libanês|Hospital Israelita Albert Einstein|Hospital Moinhos de Vento|Hospital Alemão Oswaldo Cruz|A Beneficência Portuguesa de São Paulo |
Health Care Associated Infection|Ventilator Associated Pneumonia|Central Line-associated Bloodstream Infection (CLABSI)|Catheter-Associated Urinary Tract Infection
|
August 3, 2022 | Phase 3 |
NCT02572791 | Washington University School of Medicine |
Skin and Subcutaneous Tissue Bacterial Infections|Staphylococcus Aureus|MRSA - Methicillin Resistant Staphylococcus Aureus Infection
|
October 2015 | Phase 4 |
NCT01955317 | International Centre for Diarrhoeal Disease Research, Bangladesh|State University of New York at Buffalo |
Hand Washing Behavior|Hand Cleansing Behavior|Chlorhexidine|Neonatal Period
|
October 2013 | Not Applicable |
NCT01947192 | Federal University of Pelotas |
Non-carious Cervical Lesions
|
November 2011 | Not Applicable |
NCT03955341 | Misr International University |
Patients With Deep Carious Lesions
|
October 20, 2019 | Not Applicable |
NCT04256798 | University of Birmingham |
Infection|Pneumonia|Surgical Site Infection|Wound Infection|Surgical Wound Infection|Postoperative Complications|Anesthesia|Communicable Disease|Pathologic Processes|Perioperative Complication|Chlorhexidine|Laparotomy
|
November 13, 2020 | Phase 3 |
NCT00004640 | University of Washington|National Institute of Dental and Craniofacial Research (NIDCR)|Colgate Palmolive |
Tooth Loss|Periodontal Disease|Tooth Decay
|
May 1998 | Phase 3 |
NCT03014778 | HaEmek Medical Center, Israel |
Vaginal Surgeries
|
January 1, 2017 | Phase 4 |
NCT02062047 | University of Guarulhos |
Periodontitis|Diabetes
|
December 2007 | Phase 4 |
NCT03719404 | Postgraduate Institute of Dental Sciences Rohtak |
Root Canal Infection
|
October 2016 | Not Applicable |
NCT00859235 | Hillel Yaffe Medical Center |
Dysphagia|Peristomal Wound Infection
|
May 2009 | Phase 3 |
NCT04527276 | Istanbul Medeniyet University |
Ventilator Associated Pneumonia
|
February 1, 2019 | Not Applicable |
NCT01594827 | Johns Hopkins University|Case Western Reserve University|Cystic Fibrosis Foundation |
Cystic Fibrosis
|
October 2012 | Phase 2 |
NCT05919966 | National Taiwan University Hospital |
Central Line-associated Bloodstream Infection (CLABSI)
|
April 12, 2023 | |
NCT02833376 | Universidade do Vale do Sapucai |
Anesthesia, Spinal|Anesthesia, Epidural|Antisepsis
|
May 30, 2016 | Not Applicable |
NCT04032184 | Cairo University |
Prevention of Dental Caries
|
October 1, 2019 | Not Applicable |
NCT04202471 | Northwell Health |
Surgical Site Infection
|
March 1, 2020 | Not Applicable |
NCT03475394 | KLE VK Institute of Dental Sciences |
Chronic Periodontitis
|
January 2015 | Not Applicable |
NCT02490631 | Vanderbilt University|Sage Products, Inc.|Vanderbilt University Medical Center |
Surgical Site Infections|Post Operative Complication
|
August 2015 | Phase 3 |
NCT01613365 | Assistance Publique Hopitaux De Marseille |
Infections and Respiratory Infectious
|
May 2012 | Phase 3 |
NCT01382914 | Technische Universität Dresden |
Discoloration of Teeth
|
April 2011 | Not Applicable |
NCT04679558 | Cairo University |
Caries
|
September 15, 2020 | Early Phase 1 |
NCT05844683 | Okan University |
Health Care Associated Infection|Skin
|
September 1, 2022 | Not Applicable |
NCT04516226 | Albany Medical College |
Preterm Premature Rupture of Membrane
|
August 1, 2020 | Not Applicable |
NCT01857804 | Göteborg University|The Swedish Research Council |
Peri-Implantitis
|
January 2013 | Phase 4 |
NCT01105819 | Region Skane|County Council of Halland, Sweden|Probi AB |
Pathogenic Bacteria in the Oropharynx|Ventilator-associated Pneumonia
|
April 2010 | Not Applicable |
NCT05361278 | Damascus University |
Dental Caries|Infection, Bacterial|Tooth, Deciduous
|
January 15, 2021 | Not Applicable |
NCT02950246 | Hôpital Raymond Poincaré |
Infection of Catheter Exit Site|Catheter Related Infection
|
November 2016 | Not Applicable |
NCT03438890 | Kangbuk Samsung Hospital |
Gynecologic Disease
|
April 23, 2018 | Not Applicable |
NCT01216761 | University of Michigan|Blue Cross Blue Shield of Michigan Foundation |
Bacteremia
|
May 2008 | Not Applicable |
NCT05803590 | Cairo University |
Plaque Induced Gingivitis
|
May 1, 2023 | Not Applicable |
NCT01657396 | University of Calgary|Sage Products, Inc. |
Ventilator Associated Pneumonia|Oral Hygiene
|
July 2012 | Not Applicable |
NCT05952921 | Universidad El Bosque, Bogotá |
Periodontal Diseases|Chronic Periodontitis|Microbial Colonization
|
July 10, 2019 | Not Applicable |
NCT01154530 | Herlev Hospital|Bispebjerg Hospital|University Hospital, Gentofte, Copenhagen |
Gastroscopy
|
January 2011 | Not Applicable |
NCT01528852 | Johns Hopkins Bloomberg School of Public Health|Annamalai University|Ministry of Health and Social Welfare, Zanzibar |
Neonatal Mortality|Cord Care|Omphalitis
|
October 2010 | Phase 3 |
NCT04225065 | Mark Seeley|Geisinger Clinic |
Arm Fracture|Surgical Site Infection
|
June 17, 2020 | Phase 4 |
NCT04074915 | Institute of Dental Sciences, Bareilly, Uttar Pradesh, India |
Chronic Periodontitis
|
December 20, 2018 | Not Applicable |
NCT05059145 | Karolinska Institutet |
Candidiasis, Vulvovaginal
|
April 27, 2022 | Phase 2 |
NCT05920122 | University of Pittsburgh |
Surgical Site Infection|Cesarean Section; Infection
|
July 1, 2023 | Phase 4 |
NCT04683146 | Centro Ortopedico y Quirurgico del Pie |
Antisepsis
|
March 10, 2021 | Phase 4 |
NCT05024760 | Madigan Army Medical Center|United States Department of Defense |
Peri-Implantitis|Peri-implant Mucositis|Implant Infection|Dental Implant Failed
|
July 28, 2022 | Early Phase 1 |
NCT05963711 | Hadassah Medical Organization |
Bacterial Vaginosis|Microbial Colonization
|
October 17, 2022 | Not Applicable |
NCT05913856 | National Taiwan University Hospital |
Ventilator Associated Pneumonia
|
January 4, 2022 | Not Applicable |
NCT04723446 | Queen Mary University of London|GlaxoSmithKline |
Covid19|Coronavirus
|
May 19, 2021 | Not Applicable |
NCT00759187 | Colgate Palmolive |
Gingival Diseases
|
January 2008 | Phase 3 |
NCT03174756 | Universidad El Bosque, Bogotá |
Hypochlorous Acid|Mouthwashes
|
January 15, 2015 | Phase 2 |
NCT00198679 | Johns Hopkins Bloomberg School of Public Health |
Skin Diseases, Infectious
|
March 2004 | Phase 4 |
NCT04218110 | Professional Disposables International, Inc. |
Surgical Site Infection
|
February 11, 2020 | Phase 3 |
NCT00248300 | Virginia Commonwealth University|United States Department of Defense|Uniformed Services University of the Health Sciences|TriService Nursing Research Program |
Pneumonia
|
August 2005 | Phase 4 |
NCT04223076 | University of Oslo |
Periodontal Diseases|Periodontitis|Dental Plaque
|
March 20, 2019 | Phase 4 |
NCT00123123 | State University of New York at Buffalo|National Institute of Dental and Craniofacial Research (NIDCR) |
Pneumonia
|
March 2004 | Phase 2 |
NCT03614429 | Cairo University |
Penile Prosthesis; Complications
|
June 1, 2018 | Phase 2 |
NCT03115892 | Cairo University |
Halitosis
|
April 1, 2017 | Phase 1|Phase 2 |
NCT01495117 | Seung Duk Lee|National Cancer Center, Korea |
Surgical Site Infection
|
October 2011 | Phase 3 |
NCT02033187 | Vanderbilt University |
Healthcare Associated Infections
|
July 2012 | Phase 4 |
NCT05709015 | University of Ljubljana |
Gingivitis
|
January 5, 2023 | Phase 2 |
NCT03741894 | University of Pecs |
Alveolitis of Jaw|Alveoli, Teeth; Inflammation|Dry Socket|Impacted Third Molar Tooth
|
September 1, 2018 | Phase 4 |
NCT05016713 | Cairo University |
S.Mutans Colonization in Adults With Fixed Orthodontic Appliance
|
June 1, 2021 | Not Applicable |
NCT03173053 | Radboud University Medical Center|ZonMw: The Netherlands Organisation for Health Research and Development|Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)|University College, London |
Staphylococcus Aureus|Motility Disorder
|
February 8, 2018 | Not Applicable |
NCT02479347 | Fondazione IRCCS Istituto Nazionale dei Tumori, Milano |
Wound Infection|Breast Neoplasms
|
March 2013 | Phase 4 |
NCT04603794 | Ohio State University |
COVID-19
|
October 1, 2020 | Phase 4 |
NCT04723732 | King Abdulaziz University |
Gingivitis|Dental Plaque
|
August 15, 2017 | Not Applicable |
NCT01751178 | GlaxoSmithKline |
Gingivitis
|
October 2012 | Phase 4 |
NCT04718922 | Seoul National University Hospital |
Endobronchial Ultrasound
|
January 20, 2021 | Phase 4 |
NCT05870059 | Ziauddin University |
Periodontal Diseases
|
February 2, 2022 | Phase 2 |
NCT02095535 | University of British Columbia |
Drying Time
|
April 2014 | |
NCT03940729 | Lund University |
Intravenous Drug Abuse, S Aureus Colonization
|
December 15, 2016 | Phase 4 |
NCT03001102 | Federal University of Minas Gerais|Fundação de Amparo à Pesquisa do estado de Minas Gerais |
Surgical Wound Infection
|
August 2015 | Not Applicable |
NCT04821193 | Istanbul University - Cerrahpasa (IUC) |
Disinfectant Dye Adverse Reaction|Catheter-Related Infections|Nursing Caries|Children, Only|Skin Lesion|Chlorhexidine Adverse Reaction|Catheter
|
November 7, 2017 | Not Applicable |
NCT01537783 | Tufts Medical Center |
Cutaneous Abscess
|
September 2011 | Phase 4 |
NCT02150031 | University of Santiago de Compostela |
Bacteremia|Tooth Extraction Status Nos
|
December 2010 | Phase 4 |
NCT00612469 | Universidade Federal do Ceara |
Dental Caries
|
October 2005 | Not Applicable |
NCT03064191 | rayan rabie dahab|Cairo University |
Postoperative Pain|Pain, Dental
|
September 2017 | Not Applicable |
NCT05256914 | University of Pavia |
Peri-implant Mucositis
|
February 27, 2022 | Not Applicable |
NCT03103204 | University of Taubate |
Obese|Obesity, Morbid|Periodontitis
|
January 21, 2017 | Phase 4 |
NCT05211622 | University of Palermo |
Mucositis (MeSH Unique ID: D052016)|Stomatitis (MeSH Unique ID: D013280)
|
March 10, 2022 | Phase 4 |
NCT01024738 | Colgate Palmolive |
Dental Plaque
|
March 2008 | Phase 3 |
NCT02678104 | Riyadh Colleges of Dentistry and Pharmacy |
Dry Socket
|
October 2016 | Phase 2 |
NCT02695901 | Universidade Federal de Santa Maria|Centro Universitário Franciscano |
Dental Plaque
|
March 2016 | Phase 4 |
NCT05816512 | Ahmed Yousif Mahdi|University of Baghdad |
Dental Caries|Gingivitis|Periodontitis
|
April 1, 2023 | Not Applicable |
NCT00980980 | Harvard Pilgrim Health Care|Agency for Healthcare Research and Quality (AHRQ)|Centers for Disease Control and Prevention|Hospital Corporation of America|University of California, Irvine|Department of Population Medicine, Harvard Medical School + Harvard Pilgrim Healthcare Institute |
Methicillin-resistant Staphylococcus Aureus
|
September 2009 | Not Applicable |
NCT03105960 | Cairo University |
Gingival Bleeding
|
March 10, 2017 | Not Applicable |
NCT01782573 | Changhua Christian Hospital |
Liver Tumors
|
October 2011 | Phase 4 |
NCT02990013 | University of Miami |
Cleaning Product Causing Toxic Effect
|
December 1, 2018 | Early Phase 1 |
NCT03489629 | University of North Carolina, Chapel Hill|University of Washington|Cook Children´s Medical Center|Indiana University|University of Michigan|University of Texas Southwestern Medical Center|St. Louis Children´s Hospital |
Cystic Fibrosis
|
April 3, 2018 | Phase 2 |
NCT02566928 | Clinical Directors Network|Rockefeller University|Patient-Centered Outcomes Research Institute |
Methicillin-Resistant Staphylococcus Aureus|Recurrence|Staphylococcal Skin Infections|Antibiotic Resistance
|
October 2015 | Phase 4 |
NCT01213550 | Ege University |
This Study Evaluated the Effectiveness of Chlorhexidine Mouthrinse on Subgingival Microbiota
|
March 2006 | Phase 4 |
NCT02319668 | GlaxoSmithKline |
Dental Prophylaxis and Implant Surgery
|
February 1, 2015 | Phase 4 |
NCT02502682 | Jared Brooks|Northwestern Medicine |
Clostridium Difficile
|
July 2015 | Phase 2 |
NCT01438515 | Horizon Health Network |
Methicillin-resistant Staphylococcus Aureus
|
August 2008 | Not Applicable |
NCT02546804 | Government College of Dentistry, Indore |
Gingivitis|Periodontitis
|
June 2015 | Not Applicable |
NCT03474146 | Government College of Dentistry, Indore |
Periodontal Diseases|Gingivitis|Periodontitis
|
April 12, 2017 | Not Applicable |
NCT04365270 | Ain Shams University |
Reversible Pulpitis|Pulpitis|Caries,Dental|Caries Class I|Caries; Dentin|Caries
|
January 15, 2019 | Phase 3 |
NCT04274517 | University of Southern California |
Periprosthetic Joint Infection
|
January 16, 2021 | Not Applicable |
NCT03382730 | University of Toronto|Sunnybrook Health Sciences Centre|Toronto General Hospital|University Health Network, Toronto|Unity Health Toronto|MOUNT SINAI HOSPITAL |
Mortality|Oral Health|Dryness, Mouth|Pain, Orofacial
|
December 1, 2017 | Not Applicable |
NCT02767427 | Columbia University|Orthopaedic Scientific Research Foundation Inc |
Infection|Spinal Injuries
|
February 2016 | Not Applicable |
NCT02639377 | Universidade Federal do Rio Grande do Norte |
Mucositis|Gingivitis
|
October 2012 | Phase 2 |
NCT05254288 | University of Pavia |
Periodontal Diseases
|
March 22, 2022 | Not Applicable |
NCT00471783 | University of British Columbia|Canadian Foundation for Dental Hygiene Research and Education|British Columbia Dental Hygienists´ Association (BCDHA) |
Gingivitis
|
April 2006 | Phase 3 |
NCT02479958 | University of Sao Paulo|Fundação de Amparo à Pesquisa do Estado de São Paulo |
Dental Caries
|
May 2011 | Phase 1 |
NCT03977285 | Università Vita-Salute San Raffaele |
Peri-Implantitis
|
July 2, 2018 | Not Applicable |
NCT00516360 | National Institute of Allergy and Infectious Diseases (NIAID)|University of Rochester |
Catheterization
|
July 2007 | Phase 4 |
NCT03684993 | Cairo University |
High Caries Risk Patients|Caries|Antimicrobial Effect|Side Effect
|
December 10, 2019 | Phase 2|Phase 3 |
NCT04658225 | Universidade Federal Fluminense |
Age Problem
|
August 1, 2018 | Not Applicable |
NCT02433912 | Universidade Federal Fluminense |
Gingival Recession
|
June 2002 | Phase 4 |
NCT04345744 | University of Pisa |
Periodontal Diseases|Periodontal Pocket
|
January 2016 | Not Applicable |
NCT03977298 | Università Vita-Salute San Raffaele |
Peri-Implantitis
|
July 2, 2018 | Not Applicable |
NCT03574246 | Ankara University |
Sore Throat|Nausea and Vomiting, Postoperative
|
January 10, 2018 | Phase 4 |
NCT03838575 | University of Birmingham|National Institute for Health Research, United Kingdom|University College, London |
Surgical Site Infection|Surgical Wound Infection|Surgery--Complications|Surgery
|
March 1, 2019 | Phase 3 |
NCT05084378 | Hamilton Health Sciences Corporation|McMaster University |
Periprosthetic Joint Infection|Draining Wound
|
March 11, 2022 | Phase 3 |
NCT01841242 | Centre Hospitalier Universitaire de Saint Etienne|Ministry of Health, France|CareFusion |
Heart Failure|Arrhythmia
|
April 23, 2013 | Phase 4 |
NCT00357877 | Tufts University|National Institute of Dental and Craniofacial Research (NIDCR) |
Caries, Dental
|
July 2006 | Phase 3 |
NCT01975805 | University of Southern California |
Pregnancy|Cesarean Section
|
January 2010 | Not Applicable |
NCT02215473 | University of Taubate|Fundação de Amparo à Pesquisa do Estado de São Paulo|Conselho Nacional de Desenvolvimento Científico e Tecnológico |
Gingivitis|Periodontitis
|
August 2013 | Phase 4 |
NCT02911766 | University of Oslo |
Dental Plaque|Gingivitis
|
November 2016 | Phase 4 |
NCT05468099 | University of Alberta |
Risk Reduction|Occupational Exposure|Dentist-Patient Transmission
|
March 29, 2022 | Not Applicable |
NCT03209466 | Universidad de Guanajuato |
Diabetic Foot
|
May 11, 2017 | Phase 4 |
NCT02608879 | NYU Langone Health |
Oral Mucositis|Oral Cancer
|
March 2014 | Not Applicable |
NCT01723501 | All India Institute of Medical Sciences, New Delhi|Maulana Azad Medical College|Vardhman Mahavir Medical College And Safdarjung Hospital |
Neonatal Sepsis|Neonatal Mortality Rate
|
November 2012 | Phase 2|Phase 3 |
NCT01870583 | Montefiore Medical Center |
Surgical Site Infection Following Cesarean Delivery
|
February 2013 | Not Applicable |
NCT01782404 | Wellspect HealthCare |
Bacteriuria, Intermittent Catheterization
|
January 2013 | Not Applicable |
NCT01115049 | Federico II University |
Oral Mucositis
|
February 2010 | Phase 4 |
NCT04556708 | Abant Izzet Baysal University |
Periodontal Diseases
|
April 1, 2019 | Not Applicable |
NCT02096094 | Universidad de Guanajuato|G70 antisepsis |
Bed Bathing
|
April 2014 | Phase 4 |
NCT02208154 | MJM Bonten|Paris 12 Val de Marne University|UMC Utrecht |
ICU-ecology (Multidrug Resistant Bacteria)|ICU-acquired Bacteraemia
|
December 1, 2013 | Phase 3 |
NCT05916742 | Universidade Estadual Paulista Júlio de Mesquita Filho |
Gingival Recession
|
April 15, 2022 | Not Applicable |
NCT02870062 | Universidad Autonoma de Nuevo Leon |
Healthcare Associated Infections
|
August 2016 | Phase 1 |
NCT02771704 | Kuwait University |
Dentine Caries
|
October 2015 | Not Applicable |
NCT03061916 | Cairo University |
Dental Caries
|
March 2017 | Phase 3 |
NCT02216227 | VA Office of Research and Development |
Surgical Site Infection
|
April 1, 2014 | Not Applicable |
NCT03309137 | Alison Fox-Robichaud|Dr. Richard Whitlock|Dr. Julian Owen|Pamela Benoit, RN|Hamilton Health Sciences Corporation |
Infection|Heart; Surgery, Heart, Functional Disturbance as Result|Bacteremia
|
November 19, 2017 | Not Applicable |
NCT05052775 | Ziauddin University |
Dental Caries
|
October 20, 2020 | Not Applicable |
NCT01446874 | Washington University School of Medicine |
Post-operative Pneumonia|Lung Cancer|Esophageal Cancer
|
September 22, 2011 | Phase 2|Phase 3 |
NCT01640925 | Joshua Swan|Texas Southern University|The Methodist Hospital Research Institute |
Cross Infection|Pneumonia, Ventilator-associated|Catheter-related Infections|Infection Due to Indwelling Urinary Catheter|Surgical Wound Infection
|
July 2012 | Not Applicable |
NCT00636480 | CareFusion |
Topical Antisepsis
|
October 2007 | Phase 3 |
NCT04941131 | King Abdulaziz University |
COVID-19
|
July 2021 | Phase 4 |
NCT00012688 | US Department of Veterans Affairs|Colgate-Periogard-Dentsply|VA Office of Research and Development |
Diabetes Mellitus|Poor Glycemic Control|Peridontal Disease
|
Not Applicable | |
NCT05532241 | University of Rijeka|University of Ljubljana |
Gingivitis|Malocclusion
|
November 1, 2021 | Phase 3 |
NCT05874882 | University of Baghdad |
Periodontitis
|
December 12, 2022 | Early Phase 1 |
NCT02606565 | Makerere University|Centre For International Health |
Omphalitis|Septicaemia
|
July 2016 | Phase 4 |
NCT00516906 | 3M|University of Nebraska |
Catheterization
|
October 2007 | Phase 2|Phase 3 |
NCT02598778 | Montefiore Medical Center |
Dental Caries
|
November 1, 2015 | Phase 2 |
NCT03693066 | Izmir Katip Celebi University |
Ozone|Caries
|
January 2017 | Not Applicable |
NCT03894839 | Yuzuncu Y?l University |
Candidiasis, Oral
|
October 26, 2017 | Not Applicable |
NCT02018094 | Hull University Teaching Hospitals NHS Trust|University of Hull |
Wound Infection|Amputation Wound
|
October 8, 2013 | Phase 4 |
NCT00066040 | New York University|National Institute of Dental and Craniofacial Research (NIDCR) |
Caries, Dental
|
January 2001 | Not Applicable |
NCT05787600 | University of Baghdad |
Plaque Induced Gingivitis|Mouth Diseases|Bleeding Gum|Periodontal Diseases
|
March 3, 2023 | Phase 3 |
NCT03962777 | Baskent University |
Gingivitis
|
February 9, 2019 | Not Applicable |
NCT02814279 | Universidade Estadual Paulista Júlio de Mesquita Filho |
Gingival Recession
|
February 2014 | Not Applicable |
NCT03209115 | Cairo University |
Postoperative Flare up
|
July 8, 2017 | Early Phase 1 |
NCT03737201 | Izmir Katip Celebi University|The Scientific and Technological Research Council of Turkey |
Deep Caries|Ozone
|
January 1, 2017 | Not Applicable |
NCT03639363 | University Of Perugia|Fondazione Toscana Gabriele Monasterio |
Hospital Infection
|
August 10, 2015 | Phase 4 |
NCT04328753 | University of Baghdad |
Generalized Gingivitis
|
April 1, 2020 | Phase 1|Phase 2 |
NCT05039593 | Aydin Adnan Menderes University |
Oral Complications
|
July 5, 2021 | Not Applicable |
NCT00610324 | King Edward Memorial Hospital |
Nosocomial Pneumonia|Healthcare-Associated Pneumonia|Aspiration Pneumonia|Ventilator-Associated Pneumonia
|
May 2004 | Phase 4 |
NCT04575948 | Misr International University |
Plaque, Dental|Antimicrobial|Mouthwash|Cytotoxicity
|
July 2023 | Phase 2|Phase 3 |
NCT01142934 | Catholic University of the Sacred Heart|3M|Fondazione C.N.R.+Regione Toscana G. Monasterio, Pisa, Italy |
Catheterization|Infection
|
October 2009 | Phase 4 |
NCT02547103 | Chiang Mai University|Health Systems Research Institute, Thailand |
End Stage Renal Disease|Peritoneal Dialysis
|
June 1, 2016 | Phase 4 |
NCT01083407 | Federal University of São Paulo|Fundação de Amparo à Pesquisa do Estado de São Paulo |
Ventilator Associated Pneumonia
|
June 2005 | Phase 1 |
NCT04733196 | Plovdiv Medical University |
Gingivitis
|
October 1, 2020 | Not Applicable |
NCT03553628 | Moataz Gamal Ali Abdul-Maksoud Konsouh|Cairo University |
Caries, Dental|Risk Reduction
|
August 1, 2018 | Not Applicable |
NCT02935322 | University of Oslo|Göteborg University |
Periodontal Disease|Dental Caries
|
September 2009 | Phase 4 |
NCT03855527 | Nourhan M.Aly|Alexandria University|University of Alexandria |
Dental Caries
|
January 12, 2018 | Phase 2 |
NCT02001311 | King Abdulaziz University |
Orthodontic Appliance Complication|Dental Caries
|
January 2014 | Phase 1 |
NCT03623048 | Cairo University |
Decay, Dental
|
March 2019 | Not Applicable |
NCT05846139 | Tuscan Dental Institute |
Periodontal Diseases
|
January 17, 2022 | Not Applicable |
NCT03510962 | Dr Meru S|Uttaranchal Dental & Medical Research Institute |
Saliva Altered|Oral Hygiene|pH|Tooth Structure; Disorder
|
April 25, 2018 | Not Applicable |
NCT05142969 | Shanghai Zhongshan Hospital |
Chlorhexidine|Hospital-Acquired Infection|Surgery|Intensive Care Unit
|
December 1, 2021 | Not Applicable |
NCT02510144 | University of Maryland, Baltimore |
Shoulder Infection
|
August 2015 | Not Applicable |
NCT04658355 | University of Arizona |
Vaginal Flora Imbalance
|
December 15, 2020 | Not Applicable |
NCT04373018 | Postgraduate Institute of Dental Sciences Rohtak |
Periapical Periodontitis
|
December 1, 2019 | Not Applicable |
NCT00692484 | CareFusion |
Healthy
|
October 2007 | Phase 3 |
NCT03142828 | Universidad de Murcia |
Periimplantitis
|
April 15, 2017 | Phase 4 |
NCT00947518 | All India Institute of Medical Sciences, New Delhi |
Neonatal Sepsis|Low Birth Weight
|
August 2005 | Not Applicable |
NCT05586776 | University of California, Irvine|University of California, Davis|University of California, San Francisco|University of Massachusetts, Amherst |
Surgical Site Infection
|
January 17, 2023 | Phase 4 |
NCT00908817 | Soonchunhyang University Hospital |
Tracheal Intubation
|
May 2008 | Not Applicable |
NCT01233050 | University of Pennsylvania|3M |
Colorectal Surgery
|
December 2010 | Not Applicable |
NCT02124655 | University of Santiago de Compostela|Johnson & Johnson |
Oral Biofilm|Mouthwash|Periodontitis
|
September 2012 | Phase 4 |
NCT01989416 | Mahidol University |
Antibiotic Resistant Infection
|
December 2013 | Phase 3 |
NCT03503370 | VA Office of Research and Development |
Diabetic Foot Ulcer
|
January 2, 2019 | Phase 2 |
NCT01974401 | Mashhad University of Medical Sciences |
Severe Neutropenia|Thrombocytopenia|Chemotherapy|Blood Dyscrasia Patients
|
January 2010 | Phase 2 |
NCT01893060 | University of Virginia |
Line Insertion Site|Central Line-associated Bloodstream Infection (CLABSI)
|
July 2013 | Not Applicable |
NCT03656588 | Rothman Institute Orthopaedics |
Propionibacterium Infection
|
April 16, 2018 | Not Applicable |
NCT01817075 | Children´s Oncology Group|National Cancer Institute (NCI) |
Bacterial Infection|Benign Neoplasm|Malignant Neoplasm|Methicillin-Resistant Staphylococcus Aureus Infection|Myeloid Neoplasm|Recurrent Childhood Acute Lymphoblastic Leukemia|Recurrent Childhood Acute Myeloid Leukemia
|
November 4, 2013 | Phase 3 |
NCT04373421 | Yuzuncu Y?l University |
Impacted Third Molar Tooth
|
August 15, 2018 | Phase 4 |
NCT04721626 | Medical College of Wisconsin |
Head and Neck Cancer
|
January 6, 2021 |
Liquid
Room temperature in continental US; may vary elsewhere.
Solution, -20°C, 2 years
H 2 O : 100 mg/mL ( 111.39 mM ; Need ultrasonic)
DMSO : ≥ 38 mg/mL ( 42.33 mM )
* "≥" means soluble, but saturation unknown.
Add each solvent one by one: PBS
Solubility: 100 mg/mL (111.39 mM); Clear solution; Need ultrasonic