[CAS NO. 849727-88-4] (R)-(4′-Hydroxy)-5,7-dihydroxy-4-chromanone
PRODUCTS SPECIFICATIONS [849727-88-4]
DESCRIPTION [849727-88-4]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 286.28 |
| Molecular Formula | C16H14O5 |
| SMILES | O=C1[C@H](CC2=CC=C(O)C=C2)COC3=CC(O)=CC(O)=C13 |
Summary
(R)-(4′-Hydroxy)-5,7-dihydroxy-4-chromanone, a homoisoflavonoid, has antiangiogenic activity against human retinal microvascular endothelial cells [1] .
In Vitro
(R)-(4′-Hydroxy)-5,7-dihydroxy-4-chromanone has an GI
50
value of 35.8 µM on proliferation of human retinal microvascular endothelial cells (HRECs)
[1]
.
(R)-(4′-Hydroxy)-5,7-dihydroxy-4-chromanone (10 µM, 30 µM, and 100 µM; 8 hours) significantly decreases HRECs overall tubule formation and in a dose-dependent manner
[1]
.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Shipping
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.