[CAS NO. 546-62-3] Verbascose
PRODUCTS SPECIFICATIONS [546-62-3]
DESCRIPTION [546-62-3]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 828.72 |
| Molecular Formula | C30H52O26 |
| SMILES | OC[C@@H](O1)[C@@H](O)[C@H](O)[C@]1(CO)O[C@@H](O2)[C@H](O)[C@@H](O)[C@H](O)[C@H]2CO[C@@H](O3)[C@H](O)[C@@H](O)[C@@H](O)[C@H]3CO[C@@H](O4)[C@H](O)[C@@H](O)[C@@H](O)[C@H]4CO[C@@H](O5)[C@H](O)[C@@H](O)[C@@H](O)[C@H]5CO |
Summary
Verbascose, an alacto-oligosac-charides (GOS), has potent immunostimulatory activity. Verbascose acts as a potential natural immunomodulatory agent [1] .
In Vitro
Verbascose (25, 50, 100, 200, 400 μg/mL; 12, 24, 36, 48 hours) significantly increases the viability of RAW264.7 cells
[1]
.
Verbascose has notable activity of promoting peritoneal macrophages to devour neutral red in a dose-dependent manner and exhibits its maximum activity of cell phagocytosis at a concentration of 200 μg/mL
[1]
.
Verbascose induces significant increases of NO production. Verbascose can enhance the ability of devouring neutral red of peritoneal macrophages and promote the release of nitric oxide and immune reactive molecules such as interleukin (IL)-6, IL-1β, interferon (IFN)-α, and
IFN-γ
[1]
.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
Verbascose (30, 90, 120 mg/kg/day; sc; for 8 days) at a medium dose of 90 mg/kg body weight can significantly increase the index of spleen, activity of lysozyme in spleen and serum, hemolysin level in serum, and swelling rate of earlap in the delayed type of hypersensitivity (DTH) of immunosuppressed female Kunming mice
[1]
.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
H 2 O : 250 mg/mL ( 301.67 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 1.2067 mL | 6.0334 mL | 12.0668 mL |
| 5 mM | 0.2413 mL | 1.2067 mL | 2.4134 mL |
| 10 mM | 0.1207 mL | 0.6033 mL | 1.2067 mL |