[CAS NO. 20073-24-9] 3-CPs
PRODUCTS SPECIFICATIONS [20073-24-9]
DESCRIPTION [20073-24-9]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 258.23 |
| Molecular Formula | C14H10O5 |
| SMILES | O=C(C1=CC2=CC3=C(OC=C3)C=C2OC1=O)OCC |
Summary
3-CPs is a serotype capsular polysaccharide which can interfere with antibody-mediated bacterial killing.
In Vitro
3-CPs displays protective effect against UVB damage in all concentrations tested [1] . About 50% inhibition of bacterial killing is observed when 12 ng of purified type 3 CPS is added to the OPKA. The addition of 30 μL of mouse serum post-i.p. infection with WU2 (containing 0.4 to 0.7 μg/mL released type 3 CPS) shows 26% to 52% inhibition of bacterial killing, comparable to what is observed when an equivalent amount of purified CPS is added [2] .
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
References
- [1] Silva EB, et al. Modulation of the UVB-induced lethality by furocoumarins in Staphylococcus aureus. J Photochem Photobiol B. 2014 Jan 5;130:260-3.
- [2] Silva EB, et al. Modulation of the UVB-induced lethality by furocoumarins in Staphylococcus aureus. J Photochem Photobiol B. 2014 Jan 5;130:260-3. doi: 10.1016/j.jphotobiol.2013.11.012.
- [3] Choi EH, et al. Capsular Polysaccharide (CPS) Release by Serotype 3 Pneumococcal Strains Reduces the Protective Effect of Anti-Type 3 CPS Antibodies.