[CAS NO. 58543-16-1] Rebaudioside A

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PRODUCTS SPECIFICATIONS [58543-16-1]

Catalog

SLK-S3796

Brand

Selleck

CAS

58543-16-1

DESCRIPTION [58543-16-1]

Overview

MDL	MFCD02183463
Molecular Weight	967.01
Molecular Formula	C44H70O23
SMILES	C[C@]12[C@]3([C@]4(C[C@](O[C@H]5[C@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)[C@@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@H](O)[C@@H](CO)O5)(C(=C)C4)CC3)CC[C@@]1([C@@](C(O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)=O)(C)CCC2)[H])[H]

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Concentration Volume Mass	1 mg	5 mg	10 mg
1 mM	1.0341 mL	5.1706 mL	10.3412 mL
5 mM	0.2068 mL	1.0341 mL	2.0682 mL
10 mM	0.1034 mL	0.5171 mL	1.0341 mL
50 mM	-	-	-

Description

Rebaudioside A (Stevia Extract, Reb A, Glycoside A3, Stevioside A3), an natural sweetening ingredient extracted from the stevia leaf, is used in powder or liquid form to heighten sweetening intensity and improve taste. Rebaudioside A is a steviol glycoside, α-glucosidase inhibitor with IC50 of 35.01 μg/ml.can inhibit ATP-sensitive K+-channels.

In vitro

Rebaudioside A potentiates glucose-stimulated insulin secretion on MIN6 cells. It does not shange intracellular cAMP level of isolated mouse islets. Rebaudioside A modulates the effect of glucose on insulin secretion via indirect inhibition of the KATP channels, thereby allowing β cells to depolarize and generate action potentials, events that are important for glucose-stimulated insulin secretion.

References

[1] Abudula R, et al. Diabetes Obes Metab. 2008, 10(11):1074-85.

Synonyms

Kaur-16-en-18-oic acid, 13-[(O-β-D-glucopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→3)]-β-D-glucopyranosyl)oxy]-, β-D-glucopyranosyl ester, (4α)-

Rebaudioside A

Glycoside X

Glycoside A₃, from Steviarebaudiana

4G-S

Sweetener 4G-S

Stevioside a₃

Sooolite!-Pure

Rebiana

Pure Via

Reb-A 97

RA 95

Rebaudiana a

SG 95RA50

SG 95RA85

SG 95RA60

SG 95RA70

SG 95RA80

SG 95RA90

Chrysanta AR-P

Steviafin RJ