Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
1 mg
5 mg
10 mg
1 mM
1.0341 mL
5.1706 mL
10.3412 mL
5 mM
0.2068 mL
1.0341 mL
2.0682 mL
10 mM
0.1034 mL
0.5171 mL
1.0341 mL
50 mM
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Description
Rebaudioside A (Stevia Extract, Reb A, Glycoside A3, Stevioside A3), an natural sweetening ingredient extracted from the stevia leaf, is used in powder or liquid form to heighten sweetening intensity and improve taste. Rebaudioside A is a steviol glycoside, α-glucosidase inhibitor with IC50 of 35.01 μg/ml.can inhibit ATP-sensitive K+-channels.
In vitro
Rebaudioside A potentiates glucose-stimulated insulin secretion on MIN6 cells. It does not shange intracellular cAMP level of isolated mouse islets. Rebaudioside A modulates the effect of glucose on insulin secretion via indirect inhibition of the KATP channels, thereby allowing β cells to depolarize and generate action potentials, events that are important for glucose-stimulated insulin secretion.