[CAS NO. 10284-63-6]  D-Pinitol

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PRODUCTS SPECIFICATIONS [10284-63-6]

Catelog
SLK-S3870
Brand
Selleck
CAS
10284-63-6

DESCRIPTION [10284-63-6]

Overview

MDLMFCD00216659
Molecular Weight194.18
Molecular FormulaC7H14O6
SMILESO(C)[C@@H]1[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)[C@H]1O

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM5.1499 mL25.7493 mL51.4986 mL
5 mM1.0300 mL5.1499 mL10.2997 mL
10 mM0.5150 mL2.5749 mL5.1499 mL
50 mM0.1030 mL0.5150 mL1.0300 mL

Description

D-pinitol (Methylinositol, Pinitol, 3-O-Methyl-D-chiro-inositol, D-(+)-Pinitol, Inzitol) is a naturally occurring compound derived from soy and has significant pharmacological activitites such as inhibition of the T-helpercell-1 response, antiviral, larvicidal, antiinflammatory, antihyperlipidemic, cardioprotective, inhibition of ovalbumin-induced airway inflammation and antioxidant.

In vitro

D-pinitol reduces the migration and the invasion of prostate cancer cells (PC3 and DU145) at noncytotoxic concentrations. Treatment of prostate cancer cells with D-pinitol reduces mRNA and cell surface expression of αvβ3 integrin. In addition, D-pinitol exerts its inhibitory effects by reducing focal adhesion kinase (FAK) phosphorylation, c-Src kinase activity and NF-κB activation.

In vivo

D-pinitol exerts an acute and chronically-sustained antihyperglycaemic effect in the murine STZ-induced model of hypoinsulinaemic diabetes. The mechanism of action of D-pinitol does not augment the effect of insulin but might involve an interaction with part of a cellular signalling pathway that links insulin with glucose transport.


Synonyms

D-chiro-Inositol, 3-O-methyl-
Inositol, 3-O-methyl-, D-chiro-
Pinitol, (+)-
3-O-Methyl-D-chiro-inositol
D-Pinitol
3-O-Methyl-(+)-chiro-inositol
(+)-Pinitol
D-(+)-Pinitol
Pinite (inositol derivative)
Matezit
Sennit
Pinit
Sennitol
d-Pinitol
Pinitol
Inzitol
Pinitol B
D-3-O-Methyl-chiro-inositol
Caro pinitol P
Caro Pinitol P