[CAS NO. 379270-38-9]  Tenofovir alafenamide fumarate

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PRODUCTS SPECIFICATIONS [379270-38-9]

Distributor
Catalog
SLK-S4428
Brand
Selleck
CAS
379270-38-9

DESCRIPTION [379270-38-9]

Overview

MDLMFCD28167823
Molecular Weight592.54
Molecular FormulaC25H33N6O9P
SMILESC[C@H](N[P@@](OC1=CC=CC=C1)(CO[C@H](C)CN2C=NC3=C(N)N=CN=C23)=O)C(OC(C)C)=O.O=C(O)/C=C/C(O)=O

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM1.6876 mL8.4382 mL16.8765 mL
5 mM0.3375 mL1.6876 mL3.3753 mL
10 mM0.1688 mL0.8438 mL1.6876 mL
50 mM0.0338 mL0.1688 mL0.3375 mL

Description

Tenofovir alafenamide (TAF, GS-7340) fumarate is a prodrug of tenofovir but results in significantly higher intracellular tenofovir concentrations and lower serum levels. Tenofovir alafenamide is a novel inhibitor for the treatment of HIV-1 infection.

Targets

reverse transcriptase [1]