[CAS NO. 83-34-1] Skatole

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PRODUCTS SPECIFICATIONS [83-34-1]

Catalog

SLK-S4959

Brand

Selleck

CAS

83-34-1

DESCRIPTION [83-34-1]

Overview

MDL	MFCD00005627
Molecular Weight	131.17
Molecular Formula	C9H9N
SMILES	CC=1C=2C(=CC=CC2)NC1

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Concentration Volume Mass	1 mg	5 mg	10 mg
1 mM	7.6237 mL	38.1185 mL	76.2369 mL
5 mM	1.5247 mL	7.6237 mL	15.2474 mL
10 mM	0.7624 mL	3.8118 mL	7.6237 mL
50 mM	0.1525 mL	0.7624 mL	1.5247 mL

Description

Skatole (3-methylindole, Scatole) is a mildly toxic white crystalline organic compound that occurs naturally in feces. It has a fairly broad bacteriostatic effect.

In vivo

3MI causes pulmonary edema in goats, sheep, rats, and some strains of mice. Response to 3-methylindole (3MI) varies among species. Mice recover from 3MI-induced bronchiolar epithelial injury but sustain persistent olfactory mucosal injury with scarring and epithelial metaplasia. In contrast, 3MI induces obliterative bronchiolitis in horses and ponies. It also causes severe olfactory mucosal damage and fibrosis in rodents (in addition to small airways disease).

References

[1] Doran E, et al. Chem Biol Interact. 2002, 140(1):81-92.
[2] Miller MA, et al. Vet Pathol. 2003, 40(4):363-70.

Synonyms

1H-Indole, 3-methyl-

Indole, 3-methyl-

Indole, 3-methyl-(skatole)

3-Methyl-1H-indole

3-Methylindole

Scatole

Skatol

Skatole

β-Methylindole

NSC 122024