[CAS NO. 151358-47-3]  DIM-C-pPhOH

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PRODUCTS SPECIFICATIONS [151358-47-3]

Catelog
SLK-S6799
Brand
Selleck
CAS
151358-47-3

DESCRIPTION [151358-47-3]

Overview

MDLMFCD03723253
Molecular Weight338.40
Molecular FormulaC23H18N2O
SMILESOC1=CC=C(C(C2=CNC3=C2C=CC=C3)C4=CNC5=C4C=CC=C5)C=C1

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM2.9551 mL14.7754 mL29.5508 mL
5 mM0.5910 mL2.9551 mL5.9102 mL
10 mM0.2955 mL1.4775 mL2.9551 mL
50 mM0.0591 mL0.2955 mL0.5910 mL

Description

DIM-C-pPhOH (C-DIM8, CDIM8) is a antagonist. DIM-C-pPhOH inhibits tumor growth and mTOR signaling, induces apoptosis and cellular stress. DIM-C-pPhOH reduces cell proliferation with IC50 of 13.6 μM and 13.0 μM for ACHN cells and 786-O cells, respectively.

Targets

Nur77 [1]
(786-O cells based assay)
Nur77 [1]
(ACHN cells based assay)
13.0 μM13.6 μM