Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
1 mg
5 mg
10 mg
1 mM
0.8917 mL
4.4586 mL
8.9173 mL
5 mM
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10 mM
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50 mM
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Description
SM-164 is a potent, non-peptide, cell-permeable antagonist of that targets both the BIR2 and BIR3 domains with IC50 of 1.39 nM. SM-164 induces and tumor regression.
Features
The potency of bivalent SM-164 in binding, functional, and cellular assays is 2−3 orders of magnitude higher than its corresponding monovalent Smac mimetics.