[CAS NO. 123948-87-8] Topotecan
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PRODUCTS SPECIFICATIONS [123948-87-8]
Catalog
SLK-S9321
Brand
Selleck
CAS
123948-87-8
DESCRIPTION [123948-87-8]
Overview
| MDL | MFCD00870670 |
|---|---|
| Molecular Weight | 421.45 |
| Molecular Formula | C23H23N3O5 |
| SMILES | C(C)[C@]1(O)C2=C(C(=O)N3C(=C2)C=4C(C3)=CC=5C(N4)=CC=C(O)C5CN(C)C)COC1=O |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Description
Topotecan(NSC609699,Nogitecan,SKFS 104864A) is an antineoplastic agent used to treat ovarian cancer that works by inhibiting .
Targets
| Topo I [1] |
In vitro
Topotecan exhibits inhibition of outgrowth of the highly invasive and migratory leader cells (LC) population, however, topotecan enrichs the LC subset 20% above the untreated control level.
References
Synonyms
1H-Pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-, (4S)-
1H-Pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-, (S)-
(4S)-10-[(Dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
Topotecan
Hycamptamine
SKF 104864
Topotecan lactone
SKF-S 104864
Hycamptin
NSC 609699
10-Hydroxy-9-[(dimethylamino)methyl]-(20S)-camptothecin
9-(N,N-Dimethylaminomethyl)-10-hydroxycamptothecin
(S)-Topotecan
Nogitecan
Topophore C
TopoCED
(19S)-8-[(Dimethylamino)methyl]-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.0[2,11].0[4,9].0[15,20]]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione
Potactasol
Evotopin
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