Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
1 mg
5 mg
10 mg
1 mM
3.0926 mL
15.4631 mL
30.9262 mL
5 mM
0.6185 mL
3.0926 mL
6.1852 mL
10 mM
0.3093 mL
1.5463 mL
3.0926 mL
50 mM
0.0619 mL
0.3093 mL
0.6185 mL
Description
iFSP1 is a potent, selective and glutathione-independent inhibitor of with EC50 of 103 nM. iFSP1 selectively induces in GPX4-knockout Pfa1 and HT1080 cells that overexpresses FSP1.
iFSP1 selectively induces ferroptosis in GPX4-knockout Pfa1 and HT1080 cells that overexpressed FSP1. FSP1 is expressed in most tumour cell lines, and iFSP1 treatment robustly sensitizes these cells to RSL3-induced ferroptosis.
