Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
1 mg
5 mg
10 mg
1 mM
2.7185 mL
13.5925 mL
27.1850 mL
5 mM
0.5437 mL
2.7185 mL
5.4370 mL
10 mM
0.2718 mL
1.3592 mL
2.7185 mL
50 mM
0.0544 mL
0.2718 mL
0.5437 mL
Description
iHAP1 is a well-established microtubule poison, blocks fully at 5 µM which is independent of deregulated transcription, causes marked sensitization when deleting Rod1 gene in HeLa cells.
The depletion of Rod1 and TACC3 results in sensitization to iHAP1, which is caused by chemogenic interaction between Rod1 and iHAP1. As for the RPE1‐hTERT P53−/− background, deletion of Rod1 in HeLa cells causes marked sensitization to iHAP1.
