[CAS NO. 1334850-99-5]  Mito-TEMPO

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PRODUCTS SPECIFICATIONS [1334850-99-5]

Catelog
SLK-S9733
Brand
Selleck
CAS
1334850-99-5

DESCRIPTION [1334850-99-5]

Overview

MDLMFCD26406410
Molecular Weight510.03
Molecular FormulaC29H35N2O2P.Cl
SMILES[P+](C1C=CC=CC=1)(C1C=CC=CC=1)(C1C=CC=CC=1)CC(=O)NC1CC(N(C(C1)(C)C)[O])(C)C.[Cl-]

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM1.9607 mL9.8033 mL19.6067 mL
5 mM0.3921 mL1.9607 mL3.9213 mL
10 mM0.1961 mL0.9803 mL1.9607 mL
50 mM0.0392 mL0.1961 mL0.3921 mL

Description

Mito-TEMPO (MT), a mitochondria-targeted superoxide dismutase mimetic, protects against the early phase of acetaminophen (APAP) hepatotoxicity by inhibiting peroxynitrite formation. Mito-TEMPO treatment inhibits APAP-induced expression.

Targets

RIP3 kinase [1]

In vitro

Mito-TEMPO improves blastocyst development by superoxide reduction in porcine embryos in vitro.